Correlation of pancreatic-duodenal homeobox 1 (PDX1) and mucin MUC6 or MUC5AC expression with clinicopathological factors in gastric carcinomas
| Clinicopathological factor | n | PDX1 and MUC6 | PDX1 and MUC5AC | ||||||
|---|---|---|---|---|---|---|---|---|---|
| PDX1+/MUC6+ | PDX1+/MUC6− | PDX1−/MUC6+ | PDX1−/MUC6− | PDX1+/MUC5AC+ | PDX1+/MUC5A− | PDX1−/MUC5AC+ | PDX1−/MUC5AC− | ||
| p value of PDX1 and MUC6* was analysed by the χ2 method comparing PDX1+/MUC6+ with the other reactivity types (PDX1+/MUC6−, PDX1−/MUC6+, and PDX1−/MUC6−). PDX1+/MUC5AC+ was compared with the others (PDX1+/MUC5AC−, PDX1−/MUC5AC+, and PDX1−/MUC5AC−-)†. | |||||||||
| Histological type | |||||||||
| Differentiated | 43 | 28 | 11 | 0 | 4 | 30 | 9 | 3 | 1 |
| Undifferentiated | 52 | 15 | 18 | 3 | 16 | 26 | 7 | 7 | 12 |
| p value | 0.0004* | 0.0512† | |||||||
| Depth of invasion | |||||||||
| T1 | 43 | 27 | 15 | 0 | 1 | 33 | 9 | 1 | 0 |
| T2–4 | 52 | 16 | 14 | 3 | 19 | 23 | 7 | 9 | 13 |
| p value | 0.0018* | 0.0013† | |||||||
| Lymph node metastasis | |||||||||
| Absence | 51 | 29 | 18 | 1 | 3 | 36 | 11 | 1 | 3 |
| Presence | 44 | 14 | 11 | 2 | 17 | 20 | 5 | 9 | 10 |
| p value | 0.0145* | 0.0130† | |||||||