Author (ref No) | Year | No of patients | Endoscopy type* | Mean No of endoscopies | Findings at first endoscopy | Cumul. incidence (%) of duodenal adenomas at 70–75 y | Cumul. incidence (%) of Spigelman stage IV at 70–75 y | Duodenal cancer (%) | Cumul. incidence (%) of duodenal cancer at 75 y | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Age at diagnosis of FAP | Age at endoscopy | Duodenal adenomas (%) | Spigelman stage IV (%) | |||||||||
*FV, forward viewing endoscope; SV, side viewing endoscope. | ||||||||||||
†At age 80 years. | ||||||||||||
‡At age 57 years. | ||||||||||||
Church7 | 1992 | 247 | SV+FV | 3 | 25 | 33.5 | 65 | |||||
Nugent8 | 1994 | 70 | SV | 2 | 1.4 | |||||||
Debinski9 | 1995 | 200 | 39 | 65 | 2.0 | |||||||
Heiskanen12 | 1999 | 98 | SV/FV | 3 | 54 | 2 | 97† | 30† | 4† | |||
Björk14 | 2001 | 180 | FV | 2 | 74 | 8 | 98 | 20 | 10 | |||
Kadmon16 | 2001 | 231 | FV | 58 | 1.7 | |||||||
Groves17 | 2002 | 114 | SV | 42 | 5.0 | |||||||
Present study | 368 | FV | 4 | 25 | 37 | 65 | 7 | 99 | 52 | 1.6 | 4.5‡ |