Effect of forskolin, acetylcholine, and acetylcholine in the presence of forskolin on efflux of 125I from T84 cells
| Treatment | Basal efflux rate | Peak efflux rate |
|---|---|---|
| Acetylcholine (ACh 50 μM) was given five minutes after forskolin (10 μM) to the basolateral surface. All values are apparent efflux rate constants (r/min), as described in the methods. | ||
| Data are means (SEM) (n = 9). | ||
| *p<0.05 compared with time matched basal controls. | ||
| None (n = 9) | 0.115 (0.076) | 0.092 (0.024) |
| Forskolin (n = 9) | 0.057 (0.014) | 0.231 (0.057)* |
| ACh (n = 7) | 0.102 (0.018) | 0.063 (0.011) |
| ACh in the presence of forskolin (n = 9) | 0.069 (0.012) | 0.166 (0.033)* |