Influence of family history, mutation location, sex, and history of abdominal surgery on desmoid occurrence
| Variable | No with desmoids/total No (%) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Odds ratio (95% CI) | p Value | Odds ratio (95% CI) | p Value | ||
| Proportion of family members with desmoids | |||||
| None | 18/218 (8) | 1 | 0.001 | 1 | 0.006 |
| 1–49% | 12/53 (23) | 3.25 (0.76, 13.87) | 3.69 (0.86, 15.84) | ||
| 50%+ | 20/49 (41) | 7.66 (2.53, 23.25) | 6.29 (1.84, 21.53) | ||
| Mutation location | |||||
| Before 1399 | 41/303 (14) | 1 | 0.03 | 1 | 0.007 |
| After 1399 | 9/17 (53) | 7.19 (1.27, 40.67) | 6.06 (1.64, 22.48) | ||
| Sex | |||||
| Male | 17/159 (11) | 1 | 0.04 | 1 | 0.01 |
| Female | 33/161 (20) | 2.15 (1.02, 4.65) | 2.68 (1.22, 5.89) | ||
| History of abdominal surgery | |||||
| No | 2/23 (9) | 1 | 0.35 | – | – |
| Yes | 48/297 (16) | 2.02 (0.46, 8.90) | |||