n | SLC 6A4 | α2C Del 322–325 | α2A −1291 (C→G) | Controls (%) | IBS-C (%) | IBS-D (%) | IBS-Alt (%) | CAP (%) |
---|---|---|---|---|---|---|---|---|
Wt, wild-type; Het, heterozygous; hom, homozygous polymorphism. | ||||||||
IBS-C, irritable bowel syndrome with predominant constipation; IBS-D, irritable bowel syndrome with predominant diarrhoea; IBS-Alt, irritable bowel syndrome with alternating bowel function; CAP, chronic abdominal pain. | ||||||||
58 | Wt | Wt | Wt | 31 | 24 | 28 | 12 | 5 |
59 | Wt | Wt | Het/hom | 24 | 27 | 32 | 10 | 7 |
9 | Wt | Het/hom | Wt | 22 | 44 | 33 | 0 | 0 |
7 | Wt | Het/hom | Het/hom | 29 | 0 | 42 | 29 | 0 |
126 | Het/hom | Wt | Wt | 36 | 13 | 37 | 9 | 5 |
103 | Het/hom | Wt | Het/hom | 31 | 25 | 32 | 7 | 5 |
12 | Het/hom | Het/hom | Wt | 25 | 34 | 25 | 8 | 8 |
11 | Het/hom | Het/hom | Het/hom | 18 | 46 | 18 | 18 | 0 |