Trends in incidence and manifestations of ulcerative colitis (Northern France 1988–99)
| 1988–90 (n = 618) | 1991–93 (n = 750) | 1994–996 (n = 677) | 1997–99 (n = 620) | |
|---|---|---|---|---|
| *Standardised for European Population (95% confidence interval (CI)) | ||||
| †Values are median (range 25th–75th percentiles). | ||||
| ‡Large bowel up to the caecum. | ||||
| Standardised incidence rate (/105) (95% CI)* | ||||
| All (n = 2665) | 4.2 (3.9–4.5) | 4.3 (4.0–4.7) | 3.9 (3.6–4.2) | 3.5 (3.2–3.8) |
| Men (n = 1495) | 5.0 (4.5–5.5) | 5.2 (4.7–5.7) | 4.3 (3.9–4.8) | 4.1 (3.7–4.6) |
| Women (n = 1170) | 3.5 (3.1–4.0) | 3.6 (3.2–4.0) | 3.4 (3.1–3.8) | 3.0 (2.6–3.3) |
| Nord (n = 1137) | 4.0 (3.5–4.4) | 3.9 (3.4–4.3) | 3.6 (3.2–4.0) | 3.4 (3.0–3.8) |
| Pas-de-Calais (n = 777) | 4.8 (4.2–5.5) | 5.0 (4.3–5.7) | 4.2 (3.6–4.9) | 4.1 (3.5–4.7) |
| Somme (n = 242) | 3.9 (3.0–4.9) | 5.1 (4.0–6.3) | 3.7 (2.7–4.6) | 2.0 (1.3–2.6) |
| Seine-Maritime (n = 509) | 3.8 (2.7–4.9) | 4.3 (3.6–4.9) | 4.1 (3.5–4.8) | 3.8 (3.2–4.4) |
| Symptoms (%) (n = 2665) | ||||
| Diarrhoea | 56.0 | 51.5 | 57.3 | 55.2 |
| Blood in stools | 93.1 | 92.9 | 91.9 | 90.7 |
| Abdominal pain | 48.9 | 50.2 | 58.2 | 55.6 |
| Fever | 10.2 | 8.6 | 8.2 | 8.8 |
| Extradigestive symptoms | 5.0 | 3.4 | 3.1 | 3.0 |
| Perineal | 3.1 | 1.9 | 1.5 | 1.9 |
| Age at diagnosis (y)† | 34 (26–48) | 36 (27–50) | 34 (26–47) | 35 (26–47) |
| Interval before diagnosis (months)† | 2 (1–7) | 2 (1–6) | 2 (1–6) | 2 (1–4) |
| Complete digestive investigation (%)‡ (n = 2665) | 66.5 | 66.9 | 71.2 | 78.9 |
| Location (%) (n = 3056) | ||||
| Proctitis | 29.8 | 32.7 | 28.5 | 28.7 |
| Left colon | 57.8 | 49.5 | 51.4 | 52.3 |
| Pancolitis | 12.4 | 17.8 | 20.1 | 19.1 |