Group | n | Genotype | Allele (%) | ||||
---|---|---|---|---|---|---|---|
*1/*1 | *1/*2 | *2/*2 | *1 | *2 | |||
No significant difference in allele frequencies was detected between healthy controls and alcoholic controls without cancer (pā=ā0.90). However, allele frequency of the ADH1C*1/*1 allele was found to be significantly increased in all alcoholic cancer patients compared with all alcoholic non-cancer patients (pā=ā0.011). | |||||||
1 | Alcoholic cirrhosis | 39 | 8 | 23 | 8 | 50.0 | 50.0 |
2 | Alcoholic pancreatitis | 38 | 5 | 26 | 7 | 47.4 | 52.6 |
3 | Alcoholics without organ damage | 26 | 7 | 12 | 7 | 50.0 | 50.0 |
4 | All alcoholic controls without cancer | 103 | 20 | 61 | 22 | 49.0 | 51.0 |
5 | Laryngeal cancer | 41 | 15 | 23 | 3 | 64.6 | 35.4 |
6 | Oral cancer | 16 | 6 | 9 | 1 | 65.6 | 34.4 |
7 | Oropharyngeal cancer | 8 | 2 | 5 | 1 | 56.3 | 43.7 |
8 | Hypopharyngeal cancer | 22 | 7 | 11 | 4 | 56.9 | 43.1 |
9 | Oesophageal cancer | 20 | 7 | 10 | 3 | 60.0 | 40.0 |
10 | All cancers | 107 | 37 | 58 | 12 | 61.7 | 38.3 |