Distribution of advanced or early fibrosis, divided with respect to the presence of allele 3 of the solute carrier family 11 member 1 (SLC11A1) and tumour necrosis factor (TNF) polymorphisms
| SLC11A1 allele/−238 TNF polymorphisms | Fibrosis | % Fibrosis | |
|---|---|---|---|
| F0−F2 | F3−F4 | ||
| Patients carrying allele 3 and TNF −238 A/G showed a higher proportion of advanced fibrosis than patients with allele 3 and wild-type TNF. | |||
| Pearson χ2: 14.03; p = 0.002; pc = 0.016. | |||
| Non-allele 3 TNF −238 A/G | 6 | 0 | 0 |
| Non-allele 3 TNF −238 G/G | 23 | 2 | 8 |
| Allele 3 TNF −238 A/G | 12 | 14 | 54 |
| Allele 3 TNF −238 G/G | 119 | 66 | 36 |