Table 3

 Underexpressed genes with known biological functions in CAPAN-1 conditioned compared with non-conditioned myoblasts

Muscle cDNA archive IDGene nameBiological processExpression ratio
The table lists the transcripts that were found to be downregulated in myoblasts after 16 or 26 hours of incubation with CAPAN-1 conditioned medium in comparison with myoblasts incubated with control medium (NCM).
Underexpressed both after 16 and 26 h with respect to NCM at time 02-001H02Ribosomal protein S12 (RPS12Protein biosynthesis−2.96/−3.93
Underexpressed after 16 h with respect to NCM at time 02-028H06Actin alphaControl of heart, muscle contraction−2.75
2-029C09Sorcin (SR1)Control of heart and muscle development, small molecule transport, intracellular iron storage, action potential regulation, striated muscle contraction regulation−2.67
Underexpressed after 26 h with respect to NCM at time 02-002H11Thymosin beta 10 (TMSB10)Spermatid development−2.88
2-023F10Troponin T1Muscle contraction regulation−4.33
2-027F02IGF2RSignal transduction, receptor mediated endocytosis−5.44
2-029D01Ribosomal protein L14 (RPL14)Protein biosynthesis−2.56
BL-010C12PET112LProtein biosynthesis−2.73
BL-010F12Ribosomal protein L8 (RPL8)Protein biosynthesis−3.18
Underexpressed after 16 h with respect to NCM after 16 h2-010G10VAMP5Muscle development, non-selective vesicle transport−2.53
2-017G02Low density lipoprotein related protein 1 (LRP1)Pathogenesis, lipid metabolism, cell proliferation−2.67
2-018F04Endothelial differentiation related factor 1 (EDF1)Developmental processes, cell growth and maintenance−2.85
2-036G04Filamin A, alpha (actin binding protein 280) (FLNA)Neurogenesis, cell motility, cell shape and cell size control, actin cytoskeleton reorganisation, cell surface receptor linked signal transduction−3.26
Underexpressed after 26 h with respect to NCM after 26 h2-005F09NADUFS2Complex I (NADH to ubiquinone)−2.66
BL-003C11Dual specificity phosphatase 1 (DUSP1)Oxidative stress response−4.01