Table 2

 Therapeutic regimen of all trials included in the meta-analysis

Study (reference)‡RadiotherapyChemotherapySurgery
Total dose (Gy)Fractions (No/days)Daily dose (Gy)BED
>(Gy)
BED corrected by time (Gy)DrugsDosage
>(mg/m2)
Schedules
>(day)
Interval between end of irradiation and surgery (weeks)
*Tpot squamo = 4.5 days33; †Tpotadeno = 6 days,33 α = 0.3
BED, biological equivalent dose; CDDP, cisplatin; BLM, bleomycin; 5-FU, 5-fluorouracil; VNB, vinblastin.
‡For expansion of the study names, see corresponding reference.
1Nygaard et al123520/281.7541.1226.7*CDDP201–5; 15–193
BLM5
2Le Prise et al132010/1222417.8*CDDP
5FU1001; 212.5
6002–5; 22–25
3Apinop et al144020/2824833.6*CDDP1001; 294
5FU10001–4;29–32
4Walsh et al154015/212.6750.742.6†CDDP757;422
5FU15 mg/kg1–5;36–40
5Bosset et al163710/243.750.738.4*CDDP800–2;19–212–4
6Urba et al174530/211.5×251.743.6†
>adenoca.
CDDP201–5;17–213
40.9*
>squamo.
5FU3001–21
VNB11–4;17–20