Interleukin 1β mRNA expression in the intestinal mucosa of post-infective irritable bowel syndrome (PI-IBS) and non-PI-IBS patients and controls
| Location | PI-IBS (n = 15) | Non-PI-IBS (n = 15) | Control (n = 12) | F | p Value |
|---|---|---|---|---|---|
| Values shown in the table are relative intensities of expression of each sample calculated over the intensity of β-actin expression. Expression of interleukin 1β mRNA in PI-IBS patients was significantly higher than that in non-PI-IBS patients or in controls (p<0.01). Expression was not significantly different (p>0.05) between non-PI-IBS patients and controls. | |||||
| Ileum | 2.73 (0.64) | 1.38 (0.26) | 1.50 (0.32) | 27.06 | <0.01 |
| Rectosigmoid | 2.32 (0.42) | 1.24 (0.28) | 1.27 (0.27) | 26.69 | <0.01 |