Bivariate association between survival and patient and pathology characteristics
| Characteristic | Overall survival | Cancer specific survival | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | p Value | Hazard ratio (95% CI) | p Value | |
| MSI-low, microsatellite instability low. | ||||
| 95% CI, 95% confidence interval. | ||||
| MSI-low | 0.9 (0.6–1.4) | 0.627 | 1.3 (0.7–2.2) | 0.426 |
| Male | 1.5 (1.0–2.3) | 0.049 | 1.6 (0.9–2.9) | 0.107 |
| Age 75–99 y | 2.0 (1.4–2.9) | 0.000 | 1.5 (0.9–2.5) | 0.148 |
| Rectal tumour | 1.4 (1.0–1.9) | 0.057 | 1.3 (0.8–2.1) | 0.230 |
| Tumour size ⩾5 cm | 1.2 (0.8–1.6) | 0.404 | 1.1 (0.7–1.8) | 0.634 |
| Venous invasion present | 1.9 (1.3–2.6) | 0.000 | 2.9 (1.9–4.6) | 0.000 |
| Direct spread beyond muscularis propria | 1.6 (0.9–2.7) | 0.094 | 2.3 (1.0–5.2) | 0.052 |
| Free serosal surface involved | 1.0 (0.6–1.6) | 0.995 | 1.6 (0.9–2.8) | 0.102 |
| High grade tumour | 1.7 (1.2–2.4) | 0.003 | 2.5 (1.6–4.0) | 0.000 |
| More than 3 nodes involved | 1.4 (1.0–2.0) | 0.063 | 2.2 (1.4–3.4) | 0.001 |
| Apical node involved | 2.4 (1.2–4.8) | 0.019 | 2.7 (1.0–7.3) | 0.058 |