Demographics and clinical features of the Crohn’s disease (CD), ulcerative colitis (UC), and control groups
| Crohn’s disease (n = 374) | Ulcerative colitis (n = 305) | Controls (n = 294) | |
|---|---|---|---|
| IQR, interquartile range. | |||
| Sex (M/F) | 181/193 | 171/134 | 143/151 |
| Age at diagnosis (y) (median (IQR)) | 27.8 (20.9–40.4) | 34 (25–50) | 39 (27–52) |
| Duration of follow up (y) (median (IQR)) | 11.8 (6.5–20.2) | 7.5 (3.35–13.38) | |
| Caucasian (%) | 98.7% | 98.3% | |
| CD location at diagnosis | UC disease extent | ||
| Ileal disease | 125 (36%) | Proctitis 105 (34.5%) | |
| Colonic disease | 137 (39%) | Left sided colitis 116 (37%) | |
| Ileal and colonic | 58 (14%) | Extensive colitis 84 (27.5%) | |
| Upper GI disease | 30 (8.5%) | ||
| Perianal disease | 75 (21.4%) | ||
| CD location at follow up | |||
| Ileal disease | 92 (25%) | ||
| Colonic disease | 130 (35%) | ||
| Ileal and colonic | 103 (28%) | ||
| Upper GI disease | 49 (13%) | ||
| CD behaviour at diagnosis | |||
| Inflammatory (Vienna B1) | 258 (74.8%) | ||
| Stricturing (Vienna B2) | 30 (8.4%) | ||
| Penetrating (Vienna B3) | 59 (16.8%) | ||
| CD behaviour at follow up | |||
| Inflammatory (Vienna B1) | 142 (38%) | ||
| Stricturing (Vienna B2) | 68 (18%) | ||
| Penetrating (Vienna B3) | 164 (44%) | ||