Clinical picture at diagnosis of coeliac disease and results of diagnostic procedures for the 56 reviewed patients who subsequently developed malignant lymphomas
| No of patients (%) (n = 56) | |
|---|---|
| *An antigliadin antibody test was carried out in only eight patients. | |
| †One case was not treated with a gluten free diet, and for one case information on diet effects was missing | |
| ‡A second biopsy to evaluate histological recovery was taken in 20 (36%) cases. | |
| Symptoms and signs at coeliac disease diagnosis | |
| Diarrhoea | 40 (71) |
| Weight loss | 28 (50) |
| Abdominal discomfort | 12 (21) |
| Malabsorption (iron, folate, cobalamin, xylos, etc) | 36 (64) |
| Results of diagnostic tests | |
| Villous atrophy in duodenal biopsy | 54 (96) |
| High antigliadin antibody titres | 8 (14)* |
| Symptomatic response to gluten free diet | 45 (80)† |
| Histological response to gluten free diet | 16 (29)‡ |