IL-8 −251 genotype frequencies in controls (control 1), and in patients with gastric cancer (GC), gastric ulcer (GU), duodenal ulcer (DU), and gastritis
| Genotype | Control 1 (n = 244) | GC (n = 212) | GU (n = 153) | DU (n = 130) | Gastritis (n = 195) | ||||
|---|---|---|---|---|---|---|---|---|---|
| n | OR (95% CI) | n | OR (95% CI) | n | OR (95% CI) | n | OR (95% CI) | ||
| *A/T of GC versus T/T of control: p = 0.0005. | |||||||||
| †A carrier of GC versus T/T of control: p = 0.0004. | |||||||||
| ‡A/T of GU versus T/T of control: p = 0.0053. | |||||||||
| §A/A of GU versus T/T of control: p = 0.0033. | |||||||||
| ¶A carrier of GU versus T/T of control: p = 0.0007. | |||||||||
| T/T | 149 | 93 | 1.00 | 66 | 1.00 | 68 | 1.00 | 106 | 1.00 |
| A/T | 84 | 106 | 2.02 (1.37–2.97)* | 70 | 1.88 (1.22–2.89)‡ | 57 | 1.49 (0.96–2.31) | 74 | 1.24 (0.83–1.85) |
| A/A | 11 | 13 | 1.89 (0.81–4.40) | 17 | 3.49 (1.55–7.86)§ | 5 | 1.00 (0.33–2.98) | 15 | 1.92 (0.85–4.34) |
| A carrier | 95 | 119 | 2.01 (1.38–2.92)† | 87 | 2.07 (1.37–3.12)¶ | 62 | 1.43 (0.93–2.20) | 89 | 1.32 (0.90–1.93) |