IL-8 −251 genotype frequencies in controls (control 2), and in patients with gastric cancer (GC), gastric ulcer (GU), duodenal ulcer (DU), and gastritis
| Genotype | Control 2 (n = 102) | GC (n = 212) | GU (n = 153) | DU (n = 130) | Gastritis (n = 195) | ||||
|---|---|---|---|---|---|---|---|---|---|
| n | OR (95% CI) | n | OR (95% CI) | n | OR (95% CI) | n | OR (95% CI) | ||
| *A/T of GC versus T/T of control: p = 0.011. | |||||||||
| †A carrier of GC versus T/T of control: p = 0.028. | |||||||||
| ‡A/T of GU versus T/T of control: p = 0.037. | |||||||||
| §A carrier of GU versus T/T of control: p = 0.030. | |||||||||
| T/T | 59 | 93 | 1.00 | 66 | 1.00 | 68 | 1.00 | 106 | 1.00 |
| A/T | 34 | 106 | 1.98 (1.19–3.28)* | 70 | 1.84 (1.07–3.16)‡ | 57 | 1.45 (0.84–2.52) | 74 | 1.21 (0.72–2.03) |
| A/A | 9 | 13 | 0.92 (0.37–2.28) | 17 | 1.69 (0.70–4.07) | 5 | 0.48 (0.15–1.52) | 15 | 0.93 (0.38–2.25) |
| A carrier | 43 | 119 | 1.76 (1.09–2.83)† | 87 | 1.81 (1.09–3.00)§ | 62 | 1.25 (0.74–2.11) | 89 | 1.15 (0.71–1.87) |