Table 2

 Effect of highest alcohol consumption on hepatitis C viral levels compared to non-drinkers. The results are arranged in order of decreasing effect

AuthorN1N2Effect sizeVariance95% CIp Value
N1, non-drinkers; N2, subjects consuming alcohol at the highest level in each study.
CI, confidence intervals.
Loguercio301717+3.210.27+2.17 to +4.25<0.001
Oshita223716+1.100.10+0.47 to +1.74<0.001
Poynard1710516+0.590.07+0.05 to +1.130.03
Anand281850+0.240.08−0.31 to +0.790.39
Sata241520+0.030.12−0.67 to +0.720.93
Wiley184428−0.020.06−0.50 to +0.460.92
Khan294024−0.160.07−0.67 to +0.360.54
Yoshihara263314−0.310.10−0.96 to +0.330.33
Ohnishi253510−0.480.13−1.20 to +0.240.19
Combined studies
    Fixed effects model+0.240.010+0.05 to +0.450.01
    Random effects model+0.430.143−0.31 to +1.170.29
    Test for heterogeneity<0.001