Frequency of pathogenic β-catenin mutations in the tumour types studied
| Tumour type | No studied | β-catenin mutation frequency (%) |
|---|---|---|
| One non-pathogenic mutation was identified in a sporadic adenoma and one non-pathogenic mutation in a sporadic cancer. | ||
| MSI+, microsatellite unstable; MSI−, microsatellite stable; HNPCC, hereditary non-polyposis colorectal cancer. | ||
| Sporadic adenoma | 83 | 1 (1.2) |
| Family history adenoma | 61 | 1 (1.6) |
| HNPCC adenoma | 37 | 1 (2.7) |
| Sporadic cancer, MSI− | 78 | 0 |
| Sporadic cancer, MSI+ | 34 | 0 |
| HNPCC cancer | 44 | 8 (18.2) |