Multiple logistic regression analysis examining association between hepatocellular carcinoma (HCC) and diabetes, adjusting for age, sex, race, SEER registry, and Medicare/Medicaid dual enrolment (n = 8244)
| OR | 95% CI | Wald χ2 test | p Value | |
|---|---|---|---|---|
| OR, odds ratio; 95% CI, 95% confidence interval. | ||||
| Diabetes | ||||
| No | 1.00 | – | – | Reference |
| Yes | 3.08 | 2.74–3.46 | 469.04 | <0.0001 |
| Age at HCC diagnosis | ||||
| <75 y | 1.00 | – | – | Reference |
| ⩾75 y | 0.69 | 0.62–0.77 | 40.68 | <0.0001 |
| Sex | ||||
| Female | 1.00 | – | – | Reference |
| Male | 3.70 | 3.23–4.17 | 500.99 | <0.0001 |
| Race | ||||
| White | 1.00 | – | – | Reference |
| Black | 1.27 | 1.03–1.57 | 4.88 | 0.0272 |
| Hispanic | 1.22 | 0.90–1.65 | 1.57 | 0.2096 |
| Asian | 2.37 | 1.89–2.98 | 55.17 | <0.0001 |
| Other | 2.14 | 1.67–2.73 | 36.72 | <0.0001 |
| Registry | ||||
| Atlanta | 1.00 | – | – | Reference |
| Utah | 0.62 | 0.42–0.92 | 5.55 | 0.0185 |
| Connecticut | 0.89 | 0.66–1.20 | 0.59 | 0.4419 |
| Detroit | 1.07 | 0.81–1.43 | 0.25 | 0.6204 |
| Hawaii | 0.67 | 0.45–0.99 | 4.03 | 0.0446 |
| Iowa | 0.86 | 0.63–1.16 | 0.9928 | 0.3191 |
| Los Angeles | 0.68 | 0.51–0.88 | 7.86 | 0.0050 |
| New Mexico | 0.97 | 0.69–1.38 | 0.0230 | 0.8794 |
| San Francisco | 0.71 | 0.53–0.96 | 4.88 | 0.0272 |
| San Jose | 0.65 | 0.45–0.93 | 5.49 | 0.0191 |
| Seattle | 0.89 | 0.66–1.21 | 0.5351 | 0.4645 |
| Medicare/Medicaid dual enrolment | 2.19 | 1.87–2.56 | 96.36 | <0.0001 |