Change in patient weight and nutritional status at weeks 4 and 8
| Placebo group | Thalidomide group | Absolute difference (95% CI for difference) | Significance | |
|---|---|---|---|---|
| AMA, bone free arm muscle mass. | ||||
| Weight change (kg) | ||||
| Week 4 | −2.21 | 0.37 | −2.59 (−4.3 to−0.8) | p = 0.005, t = 3.05 |
| Week 8 | −3.62 | −0.06 | −3.57 (−6.8 to−0.3) | p = 0.034, t = 2.30 |
| Change in AMA (cm3) | ||||
| Week 4 | −4.6 | 1.0 | −5.6 (−8.9 to−2.2) | p = 0.002, t = −3.39 |
| Week 8 cm3 | −8.4 | −0.5 | −7.9 (−14.0 to−1.8) | p = 0.014, t = −2.72 |
| Change in grip strength | ||||
| Week 4 | −0.88 | −1.00 | 0.125 (−2.10 to 2.35) | p = 0.909, t = 0.12 |
| Week 8 | −1.00 | −2.50 | 1.50 (−1.87 to 4.87) | p = 0.363, t = 0.93 |