Patient numbers (allele frequencies) | Crohn’s disease genotype frequencies | |||||
---|---|---|---|---|---|---|
CD | UC | HC | Wild-type | Heterozygous | Homozygous | |
HC allele frequencies differed between Edinburgh and Munich (p<0.02, odds ratio 1.35 (confidence interval 1.1–4.5)) and those between Edinburgh and Leuven approached significance (p = 0.06). | ||||||
Leuven | 334 (11.0%) | 163 (10.0%) | 139 (5.0%) | 79.3 | 19.5 | 1.2 |
Munich | 102 (7.0%) | 98 (9.0%) | 145 (4.0%) | 85.0 | 15.0 | 0 |
Edinburgh | 234 (10.3%) | 246 (6.8%) | 189 (8.8%) | 79.5 | 19.7 | 0.8 |