Hepatitis flares and fibrosis progression in chronic hepatitis C patients who underwent repeat liver biopsy
| Histological progression of hepatitis | Patients with an ALT flare (n = 16) | Patients who remained flare free (n = 36) | p Value |
|---|---|---|---|
| ALT, alanine aminotransferase. | |||
| Grading ⩾4 points | 6 (37%) | 9 (25%) | NS |
| Staging ⩾2 points | 10 (63%) | 7 (19%) | 0.003 |
| Mean fibrosis units per year | 0.414 | 0.190 | 0.02 |