BCLC stage | PST | Tumour status | Liver function status | |
---|---|---|---|---|
Tumour stage | Okuda stage | |||
Stages A and B: all criteria should be fulfilled. | ||||
Stage C: at least one criterion; *PST 1–2 or vascular invasion/extrahepatic spread. | ||||
Stage D: at least one criterion; †PST 3–4 or Okuda stage III/Child-Pugh C. | ||||
Stage A: early HCC | 0 | |||
A1 | 0 | Single, <5 cm | I | No portal hypertension and normal bilirubin |
A2 | 0 | Single, <5 cm | I | Portal hypertension and normal bilirubin |
A3 | 0 | Single, <5 cm | I | Portal hypertension and abnormal bilirubin |
A4 | 0 | 3 tumours <3 cm | I–II | Child-Pugh A–B |
Stage B: intermediate HCC | 0 | Large multinodular | I–II | Child-Pugh A–B |
Stage C: advanced HCC | 1–2* | Vascular invasion or extrahepatic spread* | I–II | Child-Pugh A–B |
Stage D: end stage HCC | 3–4† | Any | III† | Child-Pugh C† |