Univariate analysis of variables potentially predictive of survival in 268 patients with hepatocellular carcinoma HCC
| Variable | n | Mean survival (months) | p Value | |
|---|---|---|---|---|
| HCVAb, antibodies to hepatitis C virus; HBsAg, hepatitis B surface antigen; AST, aspartate aminotransferase; ALT, alanine aminotransferase; AFP, α fetoprotein; PVT, portal vein thrombosis. | ||||
| Age (y) | <65/>65 | 120/148 | 25.0/26.7 | 0.554 |
| Sex | M/F | 208/60 | 24.4/29.1 | 0.111 |
| Cirrhosis | Absent/present | 9/259 | 26.0/22.4 | 0.291 |
| HCVAb | Negative/positive | 143/125 | 26.3/23.9 | 0.344 |
| HBsAg | Negative/positive | 217/51 | 27.7/21.8 | 0.048 |
| Alcohol abuse | Yes/no | 16/252 | 24.1/26.3 | 0.289 |
| AST (UI/l) | <84/>84 | 139/129 | 27.3/24.3 | 0.060 |
| ALT (UI/l) | <85/>85 | 133/135 | 26.0/25.9 | 0.912 |
| Albumin (g/dl) | <3.5/>3.5 | 123/145 | 22.3/29.6 | <0.001 |
| Total bilirubin (mg/dl) | <1.5/>1.5 | 127/141 | 23.6/27.9 | <0.001 |
| Prothrombin activity ratio (%) | <64/>64 | 130/138 | 24.7/28.1 | 0.077 |
| Platelet count (×109/l) | <100/>100 | 133/135 | 22.0/26.5 | 0.041 |
| AFP (ng/ml) | <22.5/>22.5 | 145/123 | 29.4/22.0 | <0.001 |
| Ascites | No/yes | 234/34 | 26.6/19.3 | <0.001 |
| PVT | No/yes | 257/11 | 26.3/9.0 | <0.001 |
| Tumour size (cm) | <3.7/>3.7 | 125/143 | 26.3/21.9 | <0.001 |
| No of lesions | Single/multiple | 155/113 | 27.8/22.7 | <0.001 |