MGMT expression | Total | ||
---|---|---|---|
Undetectable/reduced | Normal | ||
Undetectable/reduced expression was assessed using immunohistochemistry for frozen tumours and western analysis for cancer cell lines. | |||
For this analysis, p = 0.05 (Fisher’s exact test). Note that the borderline association is actually in the opposite direction to that detected by Esteller and colleagues.20 | |||
K-ras mutation | |||
Absent | 40 | 17 | 57 |
Present | 19 | 18 | 37 |
Total | 59 | 35 | 94 |