Characteristics of patients according to hepatitis C virus genotype
| Genotype 1 (n = 113) | Genotype 3 (n = 28) | p Value* | |
|---|---|---|---|
| Values are median (range) or percentage. | |||
| BMI, body mass index; ALT, alanine aminotransferase; HOMA IR, homeostasis model assessment for insulin resistance. | |||
| †In 80 patients with known risk factors. | |||
| *Fisher’s exact test or Mann-Whitney test. | |||
| Age (y) | 43 (20–72) | 42.5 (30–63) | NS |
| Sex ratio (M/F) | 1.3 | 1.4 | NS |
| Disease duration (y)† | 18 (5–41) | 17 (4–25) | NS |
| Alcohol (g/day) | 0 (0–20) | 0 (0–20) | NS |
| BMI (kg/m2) | 23.6 (14–39) | 23 (19–32) | NS |
| ALT (UI/l) | 47 (11–264) | 50 (19–159) | NS |
| Viral load (106Eq/ml) | 5.9 (0.2–120) | 9.1 (0.2–104) | NS |
| Glycaemia (mm/l) | 4.7 (2.8–6.9) | 4.7 (3.6–6.7) | NS |
| Insulinaemia (µU/ml) | 5.8 (0.7–51) | 5.3 (2–30) | NS |
| C peptide (nm/l) | 0.6 (0.1–3.2) | 0.7 (0.3–1.4) | NS |
| HOMA IR | 1.2 (0.1–8.2) | 1 (0.3–6.6) | NS |
| Activity score >1 (%) | 31 | 29 | NS |
| Fibrosis score >1 (%) | 30 | 54 | 0.03 |
| % of steatosis | 0 (0–60) | 10 (0–80) | 0.0007 |
| Steatosis | |||
| <10 (%) | 71 | 40 | <0.0001 |
| 10–30 (%) | 25 | 24 | |
| >30 (%) | 4 | 36 | |