Urine wet weight, sodium and potassium
| Patient group | Total patients (n) | Patients with beneficial effect | Baseline day –3 to 0 (mean (SD)) | Effect of treatment (treatment−baseline) (mean (SD)) | Effect at follow up (follow up−baseline) (mean (SD)) | |
|---|---|---|---|---|---|---|
| Patients: 16 short bowel syndrome (SBS) patients (11 with jejunostomy and five with colon in continuity) and five rechallenged patients (all with end jejunostomy). | ||||||
| Patients Nos 03 and 15C did not complete the follow up study period. Patient No 03 had only 30% colon and was excluded from group 5 (patients with ⩾50% colon). | ||||||
| R, patients rechallenged with the same dose divided in two injections—that is, 12R is the rechallenged patient No 12. | ||||||
| Effect of treatment: paired t test; treatment versus baseline, *p<0.05, **p<0.01, ***p<0.001. | ||||||
| Effect at follow up: paired t test; follow up versus baseline, all non-significant (p>0.05). | ||||||
| Wet weight (g/day) | 1. SBS patients | 16 | 14 | 1413 (531) | 555 (485)*** | 33 (277) |
| 2. SBS patients with end jejunostomy | 10 | 8 | 1257 (339) | 680 (535)** | 11 (287) | |
| 3. SBS patients with ⩾50% colon | 5 | 5 | 1834 (663) | 461 (200)** | −90 (281) | |
| 4. SBS patients, high dietary compliance | 10 | 10 | 1509 (595) | 725 (394)*** | 30 (285) | |
| 5. Rechallenged (1st treatment) | 5 | 5 | 1071 (188) | 800 (402)* | −56 (334) | |
| 6. Rechallenged (2nd treatment) | 5 | 5 | 1231 (444) | 509 (314)* | −146 (386) | |
| Sodium (mmol/day) | 1. SBS patients | 14 | 14 | 76 (66) | 53 (40)*** | 6 (22) |
| Potassium (mmol/day) | 1. SBS patients | 14 | 10 | 36 (21) | 7 (13) | −1 (10) |