Table 6

Pancreaticoduodenectomy and pylorus or pancreas preserving duodenectomy for duodenal neoplastic lesions

Author	Treatment	Follow up	Patients	Outcome	Postoperative
*That is, wound infection, atelectasis, or urinary tract infection.
†That is, anastomotic leakage, fistula formation, wound abscess, sepsis, or pancreatitis.
NS, not stated; FAP, familial adenomatous polyposis.
Soravia⁵²	Pancreaticoduodenectomy	NS	1 FAP	Unknown	NS
Morpurgo⁴⁴	Pancreaticoduodenectomy	NS	4 FAP	No recurrence reported	Increased number of bowel movements. One patient required pouch excision and end ileostomy to control diarrhoea. 3 patients experienced weight loss, 1 patients had episodes of pancreatitis
Alarcon⁴⁶	Pancreas sparing duodenectomy	40–50 months >(mean 45.7)	3 FAP	No recurrence. Two of three patients had a small tubular adenoma in the duodenal bulb.	NS
Penna⁵⁷	Pancreaticoduodenectomy	9–108 months >(mean 42)	7 FAP severe duodenal polyposis	No recurrence in patients treated for severe duodenal polyposis.	1 pancreatic fistula, 1 upper GI haemorrhage
Penna⁵⁷	Pancreaticoduodenectomy	1–9 years	5 FAP duodenal cancer	Only 1 patients with duodenal cancer survived >4 years	Resection not possible in 2 because of peritoneal carcinomatosis or distal lymph node involvement
de Vos tot >Nederveen⁵⁸	Pancreaticoduodenectomy	7–96 months >(mean 47)	23 FAP	Recurrence in 3, 6 died of metastatic disease	5 minor morbidity*, 12 major morbidity†, 1 patient died of postoperative complications
de Vos tot >Nederveen⁵⁸	Pancreas sparing duodenectomy	2–15 months >(mean 11)	6 FAP	No recurrence	1 minor morbidity*, 3 major morbidity†
de Vos tot >Nederveen⁵⁸	Pylorus preserving duodenectomy	7–93 months >(mean 45)	12 FAP	Recurrence in 3 of 9, 3 died of metastatic disease	1 minor morbidity*, 4 major morbidity†
Ruo⁵⁹	(Pylorus preserving) pancreaticoduodenectomy	37–162 months >(mean 70.5)	7 FAP	1 patient developed jejunal adenomas 12 years after operation	1 patient developed pancreatic ascites
Chung⁶¹	Pancreas sparing duodenectomy	0.5–3 years >(mean 2.1)	4 FAP	No recurrence	1 gastric retention, 1 pancreatic fistula
Kalady[62	Pancreas sparing duodenectomy	10 years	3 FAP	1 had polyp recurrence in jejunum at 5 years of follow up	1 postoperative wound infection, 1 biliary leak
Balladur⁶³	(Pylorus preserving) pancreaticoduodenectomy	24 and 28 months	2 FAP	No recurrence	NS
Farnell⁶⁰	(Pancreas sparing) pancreaticoduodenectomy	0.3–16 years >(mean 5.6)	25 FAP and sporadic	No recurrences	10 leaks, 4 delayed gastric empytying, 1 delirium tremens, 3 abcesses. 1 patient died from bleeding and sepsis related to hepaticojejunostomy leak. Morbidity was higher after pancreas sparing duodenotomy.