Target genes searched by viral insertion
| Code | Gene/type of sequence | Full name of gene and protein | Function/protein family |
|---|---|---|---|
| ND, not determined. | |||
| Cancer associated genes | |||
| 2A-1 | hTERT | Human telomerase reverse transcriptase | Telomerase regulation |
| 2A-2 | TACC-1 | Transforming acedic coiled-coil containing protein 1 | Proto-oncogenes |
| 5A-1 | IRF2 | Interferon regulatory factor 2 | Interferon regulation |
| 7 | MUC16 | Mucin 16 | Transmembrane region and tyrosine phosphorylation site |
| 11A | PDGFRB | Platelet derived growth factor receptor beta precursor; beta platelet derived growth factor receptor | Growth factor |
| 37 | APCL | Adenomatous polyposis coli-like | APC homology |
| 41 | GA | Liver mitochondrial glutaminase/breast cell glutaminase | Glutaminase proteins/proto-oncogene |
| F2T1-4 | MLL2 | Myeloid/lymphoid or mixed lineage leukaemia 2 | Transcriptional regulator |
| F2T1-5 | MGMT | O-6-methylguanine-DNA methyltransferase | DNA reparation |
| 54T | p84 | Nuclear matrix protein p84 | Nuclear matrix protein |
| 83T-A | hTERT | Human telomerase reverse transcriptase | Telomerase regulation |
| 86T | SERCA1 | Sarco/endoplasmic reticulum calcium ATPase 1 | Calcium regulation |
| GR2 | MAPK1 | Mitogen activated protein kinase 1 | Protein kinase |
| TAN7-3 | EVER2 | Epidermodysplasia verruciformis 2 | Integral membrane protein located in the ER |
| BB3 | hTERT | Human telomerase reverse transcriptase | Telomerase regulation |
| 3T-470 | PDGFB | Platelet derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homologue) | Growth factor |
| λYH16 | MLL4 | Myeloid/lymphoid or mixed lineage leukaemia 4 | Transcriptional regulator |
| Cellular genes | |||
| 8A | FN1 | Fibronectin 1 | Cell adhesion, morphology, and surface architecture |
| 10A | NEDD4L | Ubiquitin-protein ligase NEDD4-like; neural precursor cell expressed, developmentally downregulated gene 4-like | Ubiquitin ligase |
| 10S | IRAK2 | Interleukin 1 receptor associated kinase 2 | Interleukin regulation |
| 12A-1 | NCF1 | Neutrophil cytosolic factor 1 | NADPH oxidase |
| 12A-2 | ITPR2 | Inositol 1,4,5-triphosphate receptor, type 2 | Calcium regulation |
| 14 | CCT | Chaperonin containing TCP1, subunit 8 (theta) | Cell cycle regulation |
| 15 | TCEA3 | Transcription factor Sll related protein 4 | Binds to RNA polymerase II and stimulates nuclease activity |
| 16A | SCARA3 | Scavenger receptor class A, member 3 | Apoptotic regulation |
| 100 | TRAP150 | Thyroid hormone associated protein 150 alpha | Co-activator of nuclear receptor |
| 101 | GCHFR | GTP cyclohydrolase I feedback regulatory protein | Key enzyme of tetrahydrobiopterin biosynthesis |
| F2T2-5 | BIRC3 | Baculoviral IAP repeat-containing 3 | Apoptosis inhibitor |
| T2-6 | CHML | Choroideraemia-like (Rab escort protein 2) | Geranylgeranylation of most Rab proteins |
| TN-2 | ORM1 | Orosomucoid 1 | Ubiquitin protein |
| TN-3 | BCL2L2 | BCL2-like 2 | Apoptotic regulation |
| TT-1 | RAI17 | Retinoic acid induced gene 17 | Co-regulator of androgen receptor |
| 63T | CASPR3 | Cell recognition molecule CASPR3 | Cell differentiation |
| 77T | hMCM8 | Human minichromosome maintenance protein 8 | Cell cycle regulation |
| 83T-B | SFXN5 | Sideroflexin 5 | Rab11-interacting protein |
| 95T | NTRK2 | Neutrophic tyrosine kinase receptor type 2 | Receptor for neurotrophic factor |
| FR2 | SMOC1 | SPARC related modular calcium binding 1 | Calcium regulation |
| GR1 | KIF3C | Kinesin family member 3C | Kinesin family |
| SA1 | ST3GAL IV | Alpha2,3-sialyltransferase | Cell differentiation |
| SA2 | IP3R 1 | Inositol triphosphate receptor type 1 | Calcium regulation |
| HC1707-1 | GRID2 | Glutamate receptor, ionotropic, delta 2 | Ionotropic glutamate receptor |
| MN3-3 | PDE6D | Phosphodiesterase 6D, cGMP-specific, rod, delta | Phosphodiesterase |
| Unknown proteins | |||
| 5A-2 | FLJ23027 | Hypothetical protein FLJ23027 | ND |
| 8 | LOC374740 | LOC374740 | ND |
| 9S | LOC254277 | Similar to eukaryotic translation elongation factor 1 alpha 2 | Binding of aminoacyl-tRNAs to 80S ribosomes |
| 10L | FLJ20850 | FLJ20850 | ND |
| 13A | LOC253820 | Similar to MEGF6 (Rattus norvegicus) | EGF-like domain |
| 43 | LOC402235 | Similar to Ac1147 | Rho-GEF protein and ligand for sAnk1 |
| 49 | LOC285866 | LOC285866 | ND |
| F2T2-1 | LOC169831 | Similar to Sorting nexin 7 | Receptor family with phox homology (PX) domain |
| F2T2-2 | LOC342193 | Similar to transcriptional co-repressor Sin3A; transcriptional regulator, SIN3A (yeast) | Transcription of the gene encoding luteinising hormone receptor |
| TAT6-4 | LOC376426 | Similar to v-erb-a avian erythroblastic leukaemia viral oncogene homologue 2-like | Proto-oncogene |
| FR3 | LOC222792 | Similar to 60S ribosomal protein L7A (Surfeit locus protein 3) | ND |
| FR7 | FR7 | FR7 gene | ND |
| GR2s | LOC91948 | LOC91948 | ND |
| GR3 | LOC342670 | Similar to putative protein, nematode specific (Caenorhabditis elegans) | ND |
| SA5 | LOC204740 | Similar to hypothetical protein DKFZp434F1017 | ND |
| 669Hb | LOC116166 | Similar to sorbitol dehydrogenase (L-iditol 2-dehydrogenase) | Catalyses the interconversion of polyols |
| PP5T | LOC221026 | Similar to 60S ribosomal protein L17 (L23) | ND |
| PP7T | FLJ39630 | Hypothetical protein 1–107 | ND |