Age adjusted odds ratios (ORs) and 95% confidence intervals (95% CI) for histological atrophy according to the interleukin (IL)-1B, IL-10, and tumour necrosis factor α (TNF-A) genotypes in the Helicobacter pylori positive group
| Polymorphism | H pylori positive | |||
|---|---|---|---|---|
| Case/control | OR | p Value | 95% CI | |
| IL-1B C−511T | ||||
| C/C | 26/36 | 1 | Referent | |
| C/T | 60/34 | 2.42 | 0.009 | 1.25–4.68 |
| T/T | 26/8 | 4.85 | 0.001 | 1.86–12.6 |
| IL-10 T−819C | ||||
| T/T | 44/31 | 1 | Referent | |
| C/T | 48/41 | 0.83 | 0.55 | 0.45–1.54 |
| C/C | 20/6 | 2.37 | 0.10 | 0.85–6.59 |
| TNF-A T−1031C | ||||
| T/T | 80/61 | 1 | Referent | |
| C/T | 32/17 | 1.44 | 0.29 | 0.73–2.83 |
| C/C | 0/0 | – | – | – |