Table 3

Panel marker tests measuring fibrosis in non-alcoholic fatty liver disease

Test	Components of panel	Fibrosis stage	Training or validation	n	AUC	Cut off	SENS	SPEC	PPV	NPV
AST, aspartate aminotransferase; ALT, alanine aminotransferase; HA, hyaluronic acid; TIMP-1, tissue inhibitor of metalloproteinase; PIIINP, aminoterminal peptide of procollagen III; BMI, body mass index; AUC, area under the curve; CI, confidence interval; N/S, not stated; SENS, sensitivity; SPEC, specificity; PPV, positive predictive value; NPV, negative predictive value.
HA score	Age >45, obesity, AST/ALT ratio >1, diabetes, HA	F3/4 v F0/1/2	Training	79	0.92 CI (0.85–0.98)	N/S	N/S	N/S	N/S	N/S
ELF score	Age, HA, TIMP-1, PIIINP	F3/4 v F0/1/2	Validation	61	0.87 CI (0.66–1)	0.37	89	96	80	98
					0.87 CI (0.66–1)	0.46	78	98	87	96
BAAT score	Age, BMI, ALT, serum triglycerides	F2/3/4 v F0/1	Training	93	0.84 CI (N/S)	0	100	11	33	100
					0.84 CI (N/S)	1	100	47	45	100
						2	71	80	61	86
						3	14	100	100	73
						4	0	100	0	70