Adverse events according to study group
| AZA (n = 36) | 5-ASA (n = 36) | Action | |
|---|---|---|---|
| AZA, azathioprine; 5-ASA, 5-aminosalicylic acid; AST, aspartate aminotransferase; ALT, alanine aminotransferase. ↑, once the upper limit of normal. | |||
| *p = 0.046. | |||
| Fever and headache | 1 | – | Withdrawal |
| Leuco-thrombocytopenia | 1 | – | Withdrawal |
| Leucopenia | 4 | – | Dose reduction |
| AST/ALT (↑) | 1 | – | Dose reduction |
| Epigastric pain | 2 | 1 | – |
| Dermatitis | – | 1 | – |
| Total* | 9/36 (25%) | 2/36 (6%) | |