Table 1

Crohn’s disease activity index (CDAI) in CD subjects inoculated with infective larvae (L3i). Subsequently, the five CD subjects first inoculated were reinoculated from week 27 to week 30 and four CD subjects with chronic and mostly active disease were inoculated with larvae sourced from one of the authors

ID, age (y), sex	Initial inoculation trial					Reinoculation trial
	Time (weeks)					Time (weeks)
	0–4	5–8	9–12	13–16	17–20	27	30	35	39–41	45
L3i, n 3rd stage N americanus larvae inoculated percutaneously; P, prednisone n mg/day; A, azathioprine n mg/day; M, methotrexate n mg/week.
CD1 55 M
Inoculum therapy	25 L3i					25 L3i
CDAI	79	60	89	77	68		96		93	62
CD2 46 M
Inoculum therapy	25 L3i					25 L3i
CDAI	38	114	20	68	48		30			36
CD3 41 F
Inoculum therapy	25 L3i P5 M15	P5 M15	P5 M7.5			25 L3i P5 M10	P5 M10	P5 M10	M10	M10
CDAI	46	71	85	83	90		36	30	92	95
CD4 34 M
Inoculum therapy	50 L3i P38 M30	P38 M30	P50 M30	P25 M30	P5 M30	50 L3i P5 M20	P2.5 M20	M20	P25 M30	P20 M30
CDAI	260	230	232	264	118		60	442	60	122
CD5 21 F
Inoculum therapy	50 L3i P10 M20	P10 M20	P13 M20	P10	P7.5	P5	25 L3i P5	P25 M20	P15 M20	P10 M20
CDAI	144	151	103	79	73		410	180	44	61
CD6 33 F
Inoculum therapy	50 L3i P15 M20	P10 M20	P5 M20	P5 M20	P7.5 M20
CDAI	49	32	6	29	100
CD7 33 M
Inoculum therapy	50 L3i A150	P25 A150	P5 A150	P5 A150	P8 A150
CDAI	260	114	96	125	118
CD8 46 M
Inoculum therapy	50 L3i M20	M20	M20	M20	M20
CDAI	145	159	171	152	186
CD9 44 F
Inoculum therapy	100 L3i P5 M20	P10 M20	P5 M20	P5 M20	P10 M20
CDAI	173	127	106	76	125