Table 1

 Intestinal permeability in subgroups of first degree relatives of patients with Crohn’s disease (CD-R)

nPI (Lac%/Man%)*Subjects with high permeability
*Values are median (interquartile range).
PI, permeability index (lactulose (Lac)/mannitol (Man) ratio).
CD-R (household members)480.019 (0.015–0.030)25% (12)
CD-R (non-household members)610.020 (0.017–0.034)31% (19)