| Histological subtypes of the oesophagus | Adenocarcinoma in subsites of the stomach | |||||||
| Subcohort (n = 4552) | Squamous cell carcinoma (n = 97) | Adenocarcinoma (n = 133) | Cardia (n = 163) | Distant stomach (n = 257) | NOS (n = 183) | |||
| Exposure variables | No (%) | No (%) | No (%) | No (%) | No (%) | No (%) | ||
| Sex | Men | 2221 (48.8) | 55 (56.7) | 109 (82.0) | 140 (85.9) | 177 (68.9) | 134 (73.2) | |
| Women | 2331 (51.2) | 42 (43.3) | 24 (18.0) | 23 (14.1) | 80 (31.1) | 49 (26.8) | ||
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||
| Age (years) | 61.4 (4.2) | 63.0 (4.0) | 61.8 (4.1) | 61.6 (4.0) | 63.0 (4.1) | 62.6 (4.0) | ||
| Height at baseline (cm) | Men | 176.4 (6.7) | 174.4 (6.3) | 176.0 (6.2) | 176.7 (6.2) | 174.7 (5.7) | 176.3 (7.1) | |
| Women | 165.1 (6.3) | 166.9 (7.7) | 164.5 (5.6) | 165.5 (7.0) | 165.1 (6.8) | 165.1 (7.1) | ||
| Weight at baseline (kg) | Men | 77.9 (9.5) | 73.7 (12.1) | 80.4 (10.5) | 80.5 (10.5) | 76.4 (9.2) | 76.2 (9.9) | |
| Women | 68.5 (10.3) | 67.4 (10.1) | 73.5 (13.1) | 71.0 (12.8) | 68.5 (11.1) | 69.8 (11.9) | ||
| BMI at baseline (kg/m2) | Men | 25.0 (2.6) | 24.2 (3.7) | 26.0 (3.1) | 25.7 (2.8) | 25.0 (2.7) | 24.5 (2.5) | |
| Women | 25.1 (3.6) | 24.2 (3.6) | 27.2 (4.6) | 25.9 (4.5) | 25.2 (4.2) | 25.6 (4.1) | ||
| BMI at age 20 years (kg/m2) | Men | 21.8 (2.4) | 21.8 (2.5) | 21.7 (3.2) | 22.2 (2.6) | 22.0 (2.2) | 21.8 (1.9) | |
| Women | 21.4 (2.8) | 22.1 (4.1) | 22.6 (3.1) | 21.6 (3.1) | 21.4 (2.9) | 21.5 (2.9) | ||
| Change in BMI since age | Men | 3.3 (3.0) | 2.7 (3.8) | 4.3 (3.8) | 3.6 (3.2) | 2.8 (2.7) | 2.7 (3.1) | |
| 20 years (kg/m2) | Women | 3.7 (3.7) | 2.4 (5.6) | 4.4 (4.8) | 4.1 (4.2) | 3.9 (4.1) | 4.1 (3.2) | |
| Confounding factors | No (%) | No (%) | No (%) | No (%) | No (%) | No (%) | ||
| Current smoking | Men | 812 (36.6) | 32 (58.2) | 38 (34.9) | 57 (40.7) | 83 (46.9) | 58 (43.3) | |
| Women | 494 (21.2) | 20 (47.6) | 5 (20.8) | 4 (17.4) | 17 (21.3) | 11 (22.4) | ||
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||
| Number of cigarettes/day among smokers only | Men | 16.5 (9.0) | 20.1 (9.2) | 18.8 (7.2) | 16.9 (8.1) | 14.9 (6.8) | 16.1 (8.4) | |
| Women | 13.2 (8.1) | 15.3 (10.8) | 16.6 (10.1) | 8.4 (9.4) | 12.7 (6.0) | 15.0 (8.2) | ||
| Number of years of smoking among smokers only | Men | 41.4 (8.3) | 44.9 (6.9) | 42.8 (8.5) | 43.6 (7.0) | 43.3 (7.7) | 40.5 (9.6) | |
| Women | 33.7 (10.5) | 37.0 (9.0) | 37.6 (6.6) | 34.3 (6.2) | 38.6 (9.1) | 35.3 (9.1) | ||
| No (%) | No (%) | No (%) | No (%) | No (%) | No (%) | |||
| Alcohol consumption (g/day) during the past year | Men | 1857 (83.6) | 49 (89.1) | 89 (81.7) | 121 (86.4) | 144 (81.4) | 113 (84.3) | |
| Women | 1452 (62.3) | 31 (73.8) | 15 (62.5) | 13 (56.5) | 42 (52.5) | 35 (71.4) | ||
| Median (range) | Median (range) | Median (range) | Median (range) | Median (range) | Median (range) | |||
| Alcohol consumption (g/day) among consumers only | Men | 12.3 (0.2–174.1) | 24.8 (0.3–159.8) | 13.0 (0.4–120.4) | 14.9 (0.3–88.0) | 11.4 (0.5–90.1) | 14.4 (0.4–107.6) | |
| Women | 4.4 (0.1–78.7) | 11.3 (0.6–98.2) | 7.9 (0.3–32.5) | 1.3 (0.2–48.3) | 3.9 (0.3–48.3) | 3.6 (0.2–36.9) | ||
| Fruit consumption (g/day) during the past year | Men | 133.4 (0–961.6) | 88.9 (0–417.1) | 115.8 (0–769.1) | 119.7 (0–433.2) | 123.1 (0–555.3) | 128.0 (0–991.2) | |
| Women | 175.6 (0–936.5) | 168.7 (0–441.1) | 191.6 (13.8–375.8) | 218.3 (19.6–586.5) | 165.7 (0–845.0) | 186.6 (40.0–825.5) | ||
| No (%) | No (%) | No (%) | No (%) | No (%) | No (%) | |||
| Highest level of education | Men | |||||||
| Primary school | 583 (26.2) | 20 (36.4) | 25 (22.9) | 40 (28.6) | 57 (32.2) | 50 (37.3) | ||
| Lower vocational | 461 (20.8) | 8 (14.5) | 30 (27.5) | 34 (24.3) | 45 (25.4) | 29 (21.6) | ||
| High school | 762 (34.3) | 19 (34.5) | 35 (32.1) | 42 (30.0) | 57 (32.2) | 35 (26.1) | ||
| Higher vocational/ | 403 (18.1) | 7 (12.7) | 17 (15.6) | 23 (16.4) | 15 (8.5) | 20 (14.9) | ||
| university | ||||||||
| Women | ||||||||
| Primary school | 809 (34.7) | 13 (31.0) | 5 (20.8) | 9 (39.1) | 36 (45.0) | 20 (40.8) | ||
| Lower vocational | 532 (22.8) | 10 (23.8) | 8 (33.3) | 9 (39.1) | 20 (25.0) | 13 (26.5) | ||
| High school | 768 (32.9) | 15 (35.7) | 8 (33.3) | 2 (8.7) | 16 (20.0) | 14 (28.6) | ||
| Higher vocational/ | 189 (8.1) | 3 (7.1) | 2 (8.3) | 3 (13.0) | 7 (8.8) | 2 (4.1) | ||
| university | ||||||||
| History of gastric ulcer or bleeding (yes/no) | Men | 247 (11.1) | 11 (20.0) | 8 (7.3) | 12 (8.6) | 23 (13.0) | 60 (44.8) | |
| Women | 110 (4.7) | 3 (7.1) | 2 (8.3) | 0 (0) | 6 (7.5) | 4 (8.2) | ||
Numbers may not add up to the total number of subjects because of missing values. Subjects with missing data on BMI at baseline and the first year of follow-up were excluded from the analyses.