Results of methylation specific PCR analysis and immunohistochemistry of SOCS-3 in Barrett’s lesions.
| MSP methylated bands | Protein (immunohistochemistry) | |
|---|---|---|
| MSP, methylation specific PCR. | ||
| *SOCS-3 protein was detected in one case with reduced mRNA expression as well as MSP-detectable methylated bands. | ||
| Barrett’s adenocarcinoma | 14/19 | 6/19* |
| Barrett’s high grade Intraepithelial neoplasia | 20/29 | 9/29 |
| Barrett’s low grade Intraepithelial neoplasia | 6/27 | 21/27 |
| Barrett’s mucosa | 4/30 | 26/30 |