INR, international normalisation ratio; MELD, model for end-stage liver disease; SBP, spontaneous bacterial peritonitis. | |
Data are expressed as as number (%) or mean (SD) (ranges) | |
*Other causes of end-stage liver disease were: cholestatic liver disease in 25 patients (8%), metabolic liver disease in 12 patients (4%), cryptogenic cirrhosis in 5 patients (2%), autoimmune liver disease in 3 patients (1%) and Budd–Chiari in 2 patients (1%). | |
†As defined by serum creatinine ⩾1.5 mg/dl. | |
‡All 20 patients had type 2 hepatorenal syndrome. | |
§To convert mg/dl into μmol/l multiply by 17.1. | |
¶To convert mg/dl into μmol/l multiply by 16.6. | |
Age (years) | 52 (9) (18–66) |
Sex | |
Male | 207 (67%) |
Female | 101 (33%) |
Aetiology of cirrhosis | |
Hepatitis C | 136 (44%) |
Alcohol | 80 (26%) |
Hepatitis C and alcohol | 25 (8%) |
Hepatitis B | 20 (6%) |
Other* | 47 (18%) |
Complications of cirrhosis | |
Ascites | 271 (88%) |
Controlled | 112 (41%) |
Uncontrolled | 159 (59%) |
Hepatic encephalopathy | 145 (47%) |
Variceal bleeding | 91 (29%) |
SBP | 83 (27%) |
Renal failure† | 39 (13%) |
Hepatorenal syndrome‡ | 20 (7%) |
Parenchymal renal disease | 19 (6%) |
Bilirubin (mg/dl)§ | 4.3 (5) (0.2–46) |
Albumin (g/l) | 30 (5) (17–45) |
Prothrombin time | |
Ratio | 54 (16) (14–100) |
INR | 1.5 (0.8) (1–12) |
Creatinine (mg/dl)¶ | 1.2 (0.9) (0.3–11) |
Sodium (mEq/l) | 135 (5) (111–146) |
MELD score | 18 (5) (7–48) |
Child–Pugh score | 9.3 (1.8) (5–15) |