Section 3.1 Spectrum of disease
|
Jenkins541 | UK (2001) | Commentary, review of evidence | NA | Paediatric IBD | 3 | 52 |
Cumberland et al358 | UK (not specified—circa 2003) | Survey and follow-up | 85 Practices; over 1000 cases | Infectious intestinal disease in England | 2− | 73 |
Dominitz et al783 | USA (not specified—circa 2002; data between 1987 and 1996) | Analysis of routine data | Sample taken from 746 130 births | Infants born to mothers with IBD | 2+ | 66 |
Sheridan et al745 | UK (1990) | Analysis of routine data; survey | 100 Patients; 52 clinicians | Abdominal pain and resource implications | 2− | 73 |
De Lillo and Rose784 | International (2000) | Commentary; appraisal of evidence | Around 50 articles | Bowel disorders in geriatric patients | 3 | 57 |
Hislop and Heading785 | UK (2000–01) | Survey and analysis of routine data | 53 clinicians | Impact of alcohol related disease | 2− | 61 |
Lunniss et al359 | UK (data taken between 1995 and 2002) | Analysis of patient data | 629 Patients | Faecal incontinence | 2− | 66 |
McKiernan et al373 | UK (1993–95) | Analysis of patient data; survey | 93 Cases | Biliary atresia | 2− | 64 |
Plevris et al786 | International, with emphasis on UK (1998) | Commentary; review of evidence | Around 120 articles | Management of acute liver failure | 3 | 61 |
Morris787 | International (1991) | Commentary; review of research | Around 80 articles | Non-ulcer dyspepsia | 3 | 59 |
AGA788 | USA (2001) | Review of evidence; expert commentary | Over 125 articles | Prevalence and costs of GI diseases | 2+ | 68 |
De Dombal544 | International; emphasis on UK (1994) | Commentary; review of evidence | Around 7 articles | Acute abdominal pain | 3 | 57 |
Section 3.2 Incidence (includes prevalence)
|
Jenkins541 | UK (2001) | Commentary; review of evidence | NA | Paediatric IBD | 3 | 52 |
Cumberland et al358 | UK (Not specified—circa 2003) | Survey and follow-up | 85 Practices; over 1000 cases | Infectious intestinal disease (IID) in England | 2+ | 73 |
Bodger737 | International, with emphasis on UK (2002) | Commentary; appraisal of evidence | Around 60 articles | Cost of illness of Crohn’s disease | 3 | 66 |
Hislop and Heading785 | UK (2000–01) | Survey and analysis of routine data | 53 Clinicians | Impact of alcohol related disease | 2− | 61 |
Gut Week103 | UK (2004) | Public information leaflets; commentary | NA | Digestive health in the UK | 3 | 36 |
Lunniss et al359 | UK (data between 1995 and 2002 taken) | Analysis of patient data | 629 Patients | Faecal incontinence | 2− | 66 |
Ghanchi and Rembacken789 | UK (2003) | Review of evidence; commentary | Around 130 articles | IBD | 3 | 70 |
Morris787 | International (1991) | Commentary; review of research | Around 80 articles | Non-ulcer dyspepsia | 3 | 59 |
Mamula et al790 | International; emphasis on USA (data between 1977 and 2000 taken) | Analysis of routine data | 82 Patients | IBD in children under 5 years of age | 2− | 70 |
AGA788 | USA (2001) | Review of evidence; expert commentary | Over 125 articles | Prevalence and costs of GI diseases | 2+ | 68 |
McNamara et al581 | International; emphasis on USA (2000) | Review of evidence; expert commentary | Around 70 articles | Non-ulcer dyspepsia (NUD) | 2− | 64 |
Wong et al791 | China and Hong Kong (2002) | Survey of Chinese population | 2209 Survey responses | Gastro-oesophageal reflux disease (GERD) | 2− | 80 |
Pimentel et al792 | USA (not specified—circa 2000) | Survey; analysis of patient data | 448 Patients | Small intestinal bacterial overgrowth (SIBO) and IBS | 2+ | 66 |
De Dombal544 | International; emphasis on UK (1994) | Commentary; review of evidence | Around 7 articles | Acute abdominal pain | 3 | 57 |
Loftus102 | International (2004) | Review of evidence | Around 170 articles | IBD | 2− | 59 |
Russel793 | International (2000) | Review of evidence; commentary | Around 50 articles | Incidence of IBD | 3 | 55 |
Moum and Ekbom794 | International (2002) | Review of evidence | Around 90 articles | Incidence of IBD | 3 | 55 |
Wilson et al153 | International (2003) | Systematic review | 15 Articles | Prevalence of IBD | 1 | 66 |
Farrokhyar et al795 | International (literature between 1950 and 1999 taken) | Review of evidence | Around 200 articles | Epidemiology of IBD | 1 | 66 |
Lapane et al796 | USA (data between 1992 and 1996 taken) | Analysis of patient data | 133 839 Patient records | Effect of NSAID use | 2+ | 68 |
Chiang et al797 | Australia (2001) | Analysis of patient data | 167 Patients | Acute pancreatitis management | 2+ | 68 |
Fass et al798 | USA (1992–95) | Analysis of patient data; survey | 505 Patients | Functional bowel disorders (FBD) and sleep disorders | 2− | 73 |
Parry et al799 | UK (2000–01) | Case-control study | 482 Patients | IBS and bacterial gastroenteritis | 2+ | 75 |
Bernstein et al800 | Canada and USA (data between 1984 and 1996 taken) | Analysis of data | Not specified, but a large number | Extra-intestinal diseases in IBD | 2− | 59 |
Payne and Saul801 | UK (data between 1994 and 1998 taken) | Survey and analysis of data | 12 239 Responses | Common disorders in long term illnesses | 2− | 61 |
Ruigomez et al802 | UK (1994) | Analysis of data | 2956 Patients | Follow-up of patients with IBS | 2− | 50 |
Sanders et al174 | UK (1999–2001) | Cross sectional intervention | 1200 Participants | Diagnosis of coeliac disease | 2+ | 70 |
Waddell and Hislop357 | UK (not specified—circa 1999 onwards) | Analysis of patient data | 390 Patients | Impact of alcohol related disease | 2− | 59 |
BSG574 | UK (2002) | Guidelines | NA | Guidelines for dyspepsia management | 2− | 45 |
ONS803 | UK (2001) | National data | Cancer trends between 1950 and 1999 | Cancer trends in England and Wales | 2+ | 66 |
Kennedy and Jones22 | UK (Not specified—circa 1997–2000) | Cross sectional survey | 3179 Survey responses | Prevalence of gastro-oesophageal reflux symptoms | 2− | 64 |
Watson et al144 | UK (data between 1980 and 1999 taken) | Retrospective study of patient data | 107 Patients | IBD in children | 2− | 57 |
Rockall et al91 | UK (1993) | Analysis of patient data | 4185 Cases | Incidence and mortality from GI haemorrhage | 2− | 57 |
Metcalf et al243 | UK (data between 1987 and 1994 taken) | Analysis of patient data | 160 Cases | Incidence and prevalence of primary biliary cirrhosis in Newcastle Upon Tyne | 2− | 61 |
Blower et al804 | UK (1990–91) | Analysis of routine data | 620 Cases | Upper GI disease and NSAID use | 2+ | 57 |
Sawczenko et al805 | UK (1999) | Survey | 739 Responses | Childhood IBD | 2− | 50 |
James et al238 | UK (data between 1987 and 1994 taken) | Collection and analysis of patient data | 770 Cases | Primary biliary cirrhosis | 2− | 52 |
McKay et al306 | UK (data between 1984 and 1995 taken) | Analysis of patient data | Over 10 000 cases | Acute pancreatitis | 2− | 57 |
Griffin et al806 | UK (2002) | Analysis and summary of patient data | 3361 Cases | Summary of incidence and mortality rates for upper GI cancers | 3 | 43 |
Cooper et al807 | UK (2001) | Analysis of NHS Direct data | Over 150 000 calls | Calls to NHS Direct and GI diseases | 2− | 55 |
CSCG808 | UK (2003) | Commentary | NA | Response to NICE service guidance on upper GI cancers | Guideline | 41 |
Jones809 | International (1999) | Review of evidence | Around 20 articles | Methodological considerations | 3 | 68 |
Feuer595 | International (1999) | Commentary; review of evidence | Around 20 articles | Management of intestinal obstruction | 3 | 50 |
NHS, NICE810 | UK (2004) | National commentary; guidelines; recommendations | NA | Improving the outcomes in colorectal cancer | Guideline | 70 |
South Wales Cancer Network754 | UK (2003) | Service guidelines; recommendations | NA | Configuration of services | 3 | 45 |
Aerts and Penninckx266 | Europe (2003) | Review of evidence; commentary | Around 30 articles | Burden of gallstone disease | 2− | 52 |
Ashorn811 | Europe (2003) | Review of evidence; commentary | Around 20 articles | Paediatric GI disease | 3 | 43 |
Delvaux210 | Europe (2003) | Review of evidence; commentary | Around 30 articles | Diverticular disease of the colon | 3 | 48 |
Delvaux812 | Europe (2003) | Review of evidence; commentary | Around 40 articles | Faecal incontinence | 3 | 55 |
Delvaux813 | Europe (2003) | Review of evidence; commentary | Around 30 articles | Functional bowel disorders and IBS | 3 | 50 |
McNamara319 | Europe (2003) | Review of evidence; commentary | Around 40 articles | Pancreatic disease | 3 | 50 |
Burroughs and McNamara227 | Europe (2003) | Review of evidence; commentary; | Around 30 articles | Liver disease | 3 | 50 |
Talley et al53 | USA (1987–90) | Survey of random sample of population | 328 Survey responses | Prevalence of gastrointestinal symptoms in the elderly | 2− | 70 |
Section 3.3 Mortality
|
Gut Week103 | UK (2004) | Public information leaflets; commentary | NA | Digestive health in the UK | 3 | 36 |
Munkholm814 | International (2003) | Review of evidence; commentary | Around 25 articles | Incidence and prevalence of colorectal cancer | 3 | 57 |
AGA788 | USA (2001) | Review of evidence; expert commentary | Over 125 articles | Prevalence and costs of GI diseases | 2+ | 68 |
de Dombal544 | International; emphasis on UK (1994) | Commentary; review of evidence | Around 7 articles | Acute abdominal pain | 3 | 57 |
Davis et al815 | International (1990) | Analysis of data | Data from 1968 to 1987 | International cancer mortality trends | 2− | 64 |
Stanley et al816 | International (1988) | Review of trends | Around 20 articles | Mortality trends | 2− | 59 |
Khan et al817 | International (data between 1979 and 1998 taken) | Analysis of mortality data | Not specified, but a large amount of data | Mortality trends | 2− | 57 |
Cucino and Sonnenberg818 | USA (data between 1991 and 1996 taken) | Analysis of mortality data | Data of around 5000 patient deaths | Occupational mortality | 2− | 57 |
Farrokhyar et al795 | International (literature between 1950 and 1999 taken) | Review of evidence | Around 200 articles | Epidemiology of IBD | 1 | 66 |
Maroun et al819 | Canada (not clear—circa late 1990s) | Analysis of data; review of evidence | NA; cases taken from databases | Costs of cancer management | 2− | 73 |
Fernandez et al820 | Europe (data between 1955and 1989 taken) | Analysis of data | Not specified (but a large amount) | Trends in pancreatic cancer mortality | 2+ | 61 |
La Vecchia et al821 | Europe (data between 1970 and 1996 taken) | Analysis of data | Not specified (but a large amount) | Trends in primary liver cancer mortality | 2+ | 55 |
Maheswaran et al822 | UK (1993–95) | Analysis of mortality data | Over 10 000 cases | Trends in stomach cancer | 2+ | 61 |
Taylor-Robinson et al446 | UK (data between 1968 and 1996 taken) | Analysis of mortality data | A large amount | Mortality rates from intrahepatic cholangiocarcinoma | 2− | 57 |
ONS803 | UK (2001) | National data | Cancer trends between 1950 and 1999 | Cancer trends in England and Wales | 2+ | 66 |
Payne et al823 | UK (1991) | Cross sectional survey | 3877 Survey responses | Comparison of prevalence rates | 2− | 73 |
Rockall et al91 | UK (1993) | Analysis of patient data | 4185 Cases | Incidence and mortality from GI haemorrhage | 2− | 57 |
Sharp et al824 | UK (data between 1968 and 1992) | Analysis of cancer data | Not specified, but a large amount | Cancer incidence and mortality | 2− | 50 |
Blower et al804 | UK (1990–1991) | Analysis of routine data | 620 Cases | Upper GI disease and NSAID use | 2+ | 57 |
Pye et al825 | UK (1995–1996) | Analysis of patient data | 910 Patients | Carcinoma of the oesophagus and stomach | 2− | 57 |
James et al238 | UK (data between 1987 and 1994 taken) | Collection and analysis of patient data | 770 Cases | Primary biliary cirrhosis | 2− | 52 |
McKay et al306 | UK (data between 1984 and 1995 taken) | Analysis of patient data | Over 10 000 cases | Acute pancreatitis | 2− | 57 |
Bray et al328 | Europe (1995) | Analysis of mortality data | Not specified, but a large amount | Cancer incidence and mortality | 2+ | 66 |
AUGIS826 | UK (2002) | Analysis and summary of patient data | 3361 Cases | Summary of incidence and mortality rates for upper GI cancers | 3 | 43 |
Rockall et al398 | UK (1993–94) | Collection and analysis of patient data | Over 5000 cases | Outcomes after acute upper GI haemorrhage | 2− | 57 |
Tekkis et al827 | UK (1999–2001) | Analysis of patient data | 8077 Patients | Operative mortality in colorectal cancer | 2− | 70 |
NHS, NICE671 | UK (2004) | National commentary; guidelines; recommendations | NA | Improving the outcomes in colorectal cancer | Guideline | 70 |
South Wales Cancer Network754 | UK (2003) | Service guidelines; recommendations | NA | Configuration of services | 3 | 45 |
Burroughs and McNamara227 | Europe (2003) | Review of evidence; commentary | Around 30 articles | Liver disease | 3 | 50 |
Section 3.4 Morbidity
|
Morris787 | International (1991) | Commentary; review of research | Around 80 articles | Non-ulcer dyspepsia | 3 | 59 |
Waddell and Hislop357 | UK (not specified—circa 1999 onwards) | Analysis of patient data | 390 Patients | Impact of alcohol related disease | 2− | 59 |
Payne et al828 | UK (1991) | Cross sectional survey | 3877 Survey responses | Comparison of prevalence rates | 2− | 73 |
McCulloch et al829 | UK (1999–2002) | Cohort study; analysis of patient data | 955 Patients | Mortality and morbidity in gastro-oesophageal cancer surgery | 2− | 64 |
Smith et al775 | UK (not specified—circa 2003) | Survey of people with IBS symptoms | 486 Cases | Management of IBS in primary and secondary care | 2− | 66 |
Spechler20 | International (1992) | Review of research | Around 30 articles | Epidemiology of GERD | 3 | 66 |
Section 3.5 Geographical variation
|
Talley et al830 | International (not specified—circa 1995 to 2000) | Survey of communities | Over 5000 survey responses | Classification of GI symptoms | 2− | 70 |
Wong et al791 | China and Hong Kong (2002) | Survey of Chinese population | 2209 Survey responses | Gastro-oesophageal reflux disease (GERD) | 2− | 80 |
Loftus102 | International (2004) | Review of evidence | Around 170 articles | IBD | 2− | 59 |
Russel793 | International (2000) | Review of evidence; commentary | Around 50 articles | Incidence of IBD | 3 | 55 |
Moum and Ekbom794 | International (2002) | Review of evidence | Around 90 articles | Incidence of IBD | 3 | 55 |
Farrokhyar et al795 | International (literature between 1950 and 1999 taken) | Review of evidence | Around 200 articles | Epidemiology of IBD | 1 | 66 |
Maheswaran et al822 | UK (1993–95) | Analysis of mortality data | Over 10 000 cases | Trends in stomach cancer | 2+ | 61 |
Bray et al328 | Europe (1995) | Analysis of mortality data | Not specified, but a large amount | Cancer incidence and mortality | 2+ | 66 |
Levenstein et al831 | International (data between 1991 and 1996 taken) | Survey of patients | 2002 Patients | Cross-cultural variation in patients with IBD | 2− | 75 |
Section 3.6 Socioeconomic factors
|
Dominitz et al783 | USA (not specified—circa 2002; data between 1987 and 1996) | Analysis of routine data | Sample taken from 746 130 births | Infants born to mothers with IBD | 2− | 66 |
Hislop and Heading785 | UK (2000–01) | Survey and analysis of routine data | 53 Clinicians | Impact of alcohol related disease | 2− | 61 |
Neumann and Cooper32 | UK (data between 1989 and 1996 taken) | Analysis of patient data | 1101 Patients | Ethnic differences in gastro-oesophageal disease | 2− | 68 |
Wong et al791 | China and Hong Kong (2002) | Survey of Chinese population | 2209 Survey responses | Gastro-oesophageal reflux disease (GERD) | 2− | 80 |
Loftus102 | International (2004) | Review of evidence | Around 170 articles | IBD | 2− | 59 |
Longobardi et al832 | USA (1999) | Analysis of data | 23 649 Records | Work losses due to IBD | 2− | 66 |
Longobardi et al833 | Canada (1999) | Analysis of data | 23,649 Records | Work losses due to IBD | 2− | 66 |
Fass et al798 | USA (1992–95) | Analysis of patient data; survey | 505 Patients | Functional bowel disorders (FBD) and sleep disorders | 2− | 73 |
Danese et al834 | International (2004) | Expert commentary; summary of evidence | Around 40 articles | IBD and environmental factors | 3 | 48 |
Payne and Saul801 | UK (data between 1994 and 1998 taken) | Survey and analysis of data | 12 239 Responses | Common disorders in long term illnesses | 2− | 61 |
Kennedy and Jones22 | UK (not specified—circa 1997–2000) | Cross sectional survey | 3179 Survey responses | Prevalence of gastro-oesophageal reflux symptoms | 2− | 64 |
McKinney et al835 | UK (data between 1960 and 1990) | Analysis of cancer data | Not specified, but a large number | Oesophageal and gastric cancer incidence | 2− | 52 |
Bray et al328 | Europe (1995) | Analysis of mortality data | Not specified, but a large number | Cancer incidence and mortality | 2+ | 66 |
Dean et al836 | USA (1999) | Survey of patients | 11 604 Responses | Work productivity and gastro-oesophageal reflux disease (GERD) | 2− | 75 |
Bernstein et al837 | Canada (1995–96) | Survey and analysis of patient data | Not clear, but a large number | Socioeconomic factors associated with IBD | 2− | 55 |
Sands et al552 | USA (patients between 1991 and 1997) | Analysis of patient data | 345 Patients | Risk of early surgery for Crohn’s disease | 2+ | 64 |
Vaughn et al838 | UK (not specified—circa 1998) | Survey of patients and their relatives | Not clear—around 29 patients | Expressed emotion during the course of IBD | 2− | 59 |
Crane and Martin839 | UK (not specified—circa 2002) | Survey of patients | 58 Patients | Social learning, affective state, and passive coping in IBD and IBS | 2− | 68 |
Sewitch et al534 | Canada (Not specified—circa 2001) | Survey of patients and physicians | 10 Gastroenterologists and 200 patients | Patient-physician correlates in IBD | 2− | 75 |
Casati and Toner840 | International (2000) | Review of evidence; commentary | Around 70 articles | Psychosocial aspects of IBD | 3 | 55 |
Sewitch et al841 | Canada (1999) | survey of patients | 200 Patients | Psychosocial aspects in IBD | 3 | 70 |
Soo et al842 | International (studies from 1966 to present) | Systematic review | 4 Studies | Psychological interventions for non-ulcer dyspepsia | 2− | 80 |
Guthrie843 | International (2002) | Review of evidence | 3 Studies | Psychodynamic-interpersonal therapy for functional bowel disorders | 3 | 52 |
Kisely844 | UK (1996–97) | Analysis of patient data | 65 204 Patient records | Multiple readmissions | 2− | 59 |
Moum585 | International (2000) | Review of evidence | Around 80 articles | Medical treatment for IBD | 3 | 64 |
Tojek et al845 | USA (not specified—circa 2000) | Survey of patients | 62 Patients | Health status in IBD | 2− | 75 |
Jahnsen et al846 | Norway (not specified—circa 2003) | Population based study | 60 Patients | Body composition in patients with IBD | 2+ | 66 |
de Rooy et al687 | Canada (not specified—circa 2001) | Survey of patients | 259 Patients | Concerns of patients with IBD | 2− | 68 |
Ward et al738 | International (circa 1998) | Review of evidence | Around 40 articles | Management of IBD | 2− | 70 |
Hatch847 | Not specified—appears to be USA (circa 1996) | Case study | 2 Patients | Treatment of bowel obsessions | 3 | 70 |
Guthrie et al848 | UK (not specified—circa 2003) | Survey of patients; analysis of patient data | 107 Patients | Cluster analysis to define patient subgroups for IBS | 2− | 75 |
Drossman849 | International (1999) | Review of evidence | Around 40 articles | Psychosocial factors in IBS | 3 | 66 |
Payne et al823 | UK (1991) | Survey of population in Rotherham | 3877 Survey responses | Deprivation and morbidity | 2− | 70 |
Section 3.7 Quality of life
|
Pachler and Wille-Jorgensen850 | International (2002–03 (no restriction on date of studies) | Systematic review | 8 Studies | Quality of life (QoL) after rectal resection for cancer | 1 | 75 |
Yacavone et al851 | International (review of evidence: 1966 to 1999) | Review of evidence | Around 80 articles | QoL in gastroenterology | 2+ | 68 |
Simren et al852 | Sweden (not specified—circa 2002) | Survey of patients | 83 Patients | QoL in IBD | 2− | 66 |
Rubin et al676 | UK (not specified—circa 2003) | Survey of patients | 409 Responses | QoL in IBD | 2− | 68 |
Halder et al450 | USA (not specified—circa 2003) | Case-control study | 112 Patients; 110 controls | GI disorders and QoL | 2+ | 66 |
Hahn et al853 | UK and USA (not specified—circa 1999) | Survey of patients | Around 600 patients | Impact of IBS on QoL | 2− | 66 |
Blondel-Kucharski et al854 | France (not specified—circa 2001) | Survey of patients | 231 Patients | QoL in Crohn’s disease | 2− | 66 |
Akehurst et al740 | UK (1998) | Survey of patients | 161 Patients | QoL and cost impact of IBS | 2+ | 77 |
Gonsalkorale et al855 | UK (not specified—circa 2002) | Survey of patients | 78 Patients | Cognitive change in patients during IBS | 2− | 70 |
Moayyedi and Mason747 | UK (1992–94) | Analysis of patient data; survey of patients | Not clear; over 8000 patients | Economic consequences of dyspepsia | 3 | 82 |
Borgaonkar and Irvine447 | International (2000) | Review of evidence between 1966 and 1999 | Around 140 articles | QoL measurement in gastrointestinal and liver disorders | 2+ | 80 |
El-Serag et al856 | International (2001) | Systematic review of evidence between 1980 and 2001 | 17 articlesArticles | QoL of people with IBS | 1+ | 77 |
Koloski et al449 | Australia (not clear—circa 1996–2000) | Survey of random sample of population | 2910 Survey respondents | Impact of functional GI disorders on QoL | 2− | 70 |
O’Keefe et al857 | USA (1987–90) | Survey of random sample of population | 530 Survey responses | Bowel disorders and its impact on QoL in the elderly | 2− | 75 |
Gralnek et al858 | USA (1994–1998) | Survey of patients | 877 Patients | Impact of IBS on health related QoL | 2− | 73 |
Section 4.1 Care pathways
|
McNamara et al581 | International; emphasis on USA (2000) | Review of evidence; expert commentary | Around 70 articles | Non-ulcer dyspepsia (NUD) | 2− | 64 |
Association of Coloproctology of GB and Ireland505 | UK (2001) | Specification of guidelines | NA | Guidelines for the management of colorectal cancer | Guideline | 61 |
CSCG808 | UK (2003) | Commentary | NA | Response to NICE service guidance on upper GI cancers | Guideline | 41 |
Pfau et al859 | USA (1997–1999) | Implementation of care pathway | 421 patients | Clinical care pathway for the management of acute nonvariceal upper GI bleeding | 2− | 77 |
Kisely844 | UK (1996–1997) | Analysis of patient data | 65204 patient records | Multiple readmissions | 2− | 59 |
Feuer595 | International (1999) | Commentary; review of evidence | Around 20 articles | Management of intestinal obstruction | 3 | 50 |
Section 4.2 Workforce
|
Garvican607 | UK (1998) | Commentary; cost analysis | NA | Colorectal cancer screening | 3 | 70 |
Duff et al506 | UK (2002) | Audit | 65 Patients | Waiting times for treatment of rectal cancer in northwest England | 3 | 52 |
Slade et al860 | UK (not specified—circa 1998) | Survey of patients; treatment intervention | 232 Patients | Serological testing for H pylori to reduce workload | 2− | 61 |
Lamy and McNamara861 | Europe (data between 1996 and 2001) | Survey of experts | Not clear—around 25 European countries | Gastroenterology and hepatology services in Europe | 3 | 59 |
Association of Coloproctology of GB and Ireland753 | UK (2001) | Analysis of audit data; expert commentary and recommendations | 8 Main sources of audit data | Resources for coloproctology | 3 | 52 |
Section 4.3.1 Primary care
|
Cumberland et al358 | UK (not specified—circa 2003) | Survey and follow-up | 85 Practices; over 1000 cases | Infectious intestinal disease (IID) in England | 2+ | 73 |
Section 4.3.2 Inpatients
|
Hislop and Heading785 | UK (2000–01) | Survey and analysis of routine data | 53 Clinicians | Impact of alcohol related disease | 2− | |
Waddell and Hislop357 | UK (Not specified—circa 1999 onwards) | Analysis of patient data | 390 patients | Impact of alcohol related disease | 2− | |
Section 4.3.3 Outpatients
| |
Rayner et al862 | UK (1997–98) | Analysis of patient data | 1203 Patients | Outpatient review practices | 2− | 57 |
Section 4.3.4 Procedures
|
Westbrook et al863 | Australia (data between 1986 and 1990 taken) | Analysis of patient data | Unclear—over 17 000 cases | Upper GI tract investigations in the elderly | 2− | 61 |
Grassi864 | Italy (data between 1991 and 1999) | Commentary on data | Not clear, but a large number | Endoscopy activity | 4 | 36 |
BSG865 | UK (1987) | Commentary; review of evidence | Around 20 articles | Requirements for colonoscopy | 3 | 57 |
Section 4.6.1 Access
|
Froehlich et al500 | Switzerland; comparisons with UK (1994–95) | Review of evidence; analysis of patient data | 8135 Patients | Overuse of upper GI endoscopy in primary care | 2− | 61 |
Gralnek501 | International (2002) | Commentary | NA | Outpatient management of low risk non-variceal upper GI haemorrhage | 4 | 50 |
Silcock and Bramble502 | UK (1994) | Survey | 333 Responses | Survey of current practice in open access gastroscopy (OAG) | 2− | 68 |
Section 4.6.2 Inequalities
|
Watt503 | UK (2002) | Commentary | NA | The inverse care law | 4 | 39 |
Section 4.6.3 Waiting lists
|
Association of Coloproctology of GB and Ireland505 | UK (2001) | Specification of guidelines | NA | Guidelines for the management of colorectal cancer | Guideline | 61 |
Flashman et al507 | UK (2000–01) | Audit | 249 Patients | Two week standard for bowel cancer | 2− | 61 |
Duff et al506 | UK (2002) | Audit | 65 Patients | Waiting times for treatment of rectal cancer in northwest England | 3 | 52 |
Parente et al866 | Italy (1999–2000) | Audit | 142 Patients | Audit of gastroscopy | 2− | 61 |
Dunnill and Pounder504 | UK (articles between 1966 and 2002) | Literature review | Around 40 articles | Outpatient services | 2− | 70 |
Hellier508 | UK (1999–2001) | Survey of GI units | 210 GI units | Two week target for investigation cancer patients | 3 | 55 |
Section 4.6.4 Patient safety
|
Van Kouwen et al522 | Netherlands (1994–98) | Analysis of endoscopy services and patient data | 218 Patients | Upper GI endoscopy for older patients | 2− | 57 |
Navarro and Hanauer509 | International (2003) | Review of evidence; commentary | Around 70 articles | Safe treatment for IBD | 3 | 59 |
Akehurst and Kaltenthaler510 | International (trials between 1987 and 1998) | Review of RCTs | 45 RCTs | Treatment of IBS | 1 | 66 |
Dick et al511 | UK (2002) | Analysis of prescriptions | 308 Patientsand 777 prescriptions | Use of unlicensed and off-label drugs in paediatric GI diseases | 2− | 61 |
Chan and Graham512 | International (2004) | Review of evidence | Around 60 articles | Prevention of NSAID GI complications | 3 | 73 |
Sheen and Colin-Jones513 | International; emphasis on UK (2001) | Review of evidence | Around 100 articles | Over-the-counter drugs for GI diseases | 3 | 68 |
Abbas et al520 | Not specified—circa 2003) | Survey of patients; analysis of patient data | 1287 Patients | Outpatient upper GI endoscopy | 2− | 64 |
Bloor and Maynard514 | UK (1996) | Review of evidence | Around 40 articles | Prescription of NSAIDs | 3 | 73 |
Feagan515 | International (2003) | Review of evidence | Around 90 articles | Maintenance treatment for IBD | 2+ | 61 |
Ripamonti et al526 | International (1993) | Literature review | Around 40 articles | Management of bowel obstruction in patients with cancer | 2− | 75 |
Cook et al517 | International (articles from 1966 onwards) | Meta-analysis | 30 RCTs | Endoscopic therapy for acute non-variceal upper GI haemorrhage | 1 | 73 |
Page et al524 | USA (Patientsbetween 1989 and 1999) | Analysis of patient data | Over 100 patients | Surgical risk in elderly patients with IBD | 2− | 59 |
Moorthy et al525 | UK (data between 1991 and 2001) | Analysis of patient data | 48 Patients | Patients undergoing laparoscopic surgery for Crohn’s disease | 2− | 64 |
Yim et al527 | Not specified—probably USA (1996–99) | Analysis of patient data | 29 Patients | Enteral stents for patients with upper GI obstruction | 2+ | 64 |
Heuschkel et al518 | USA and UK (2000) | Survey of patients | 208 Survey responses | Complementary medicine used by children for IBD | 2− | 80 |
Quine et al521 | UK (1991) | Survey of clinicians | 39 Hospitals; 383 clinicians | Audit of upper GI endoscopy | 2− | 64 |
Section 4.6.5 Information to patients and practitioners
|
Dick et al511 | UK (2002) | Analysis of prescriptions | 308 Patients and 777 prescrip-tions | Use of unlicensed and off-label drugs in paediatric GI diseases | 2− | 61 |
Sheen and Colin-Jones513 | International; emphasis on UK (2001) | Review of evidence | Around 100 articles | Over-the-counter drugs for GI diseases | 3 | 68 |
Sewitch et al534 | Canada (not specified—circa 2001) | Survey of patients and physicians | 10 Gastroenterologists and 200 patients | Patient-physician correlates in IBD | 2− | 75 |
Stone et al141 | UK (2002) | Analysis of patient data | Over 86 000 patients | Management of IBD | 2− | 73 |
Sewitch et al535 | Canada (1999) | Survey of patients and clinicians | 10 Clinicians; 153 patients | Patient non-adherence to medication in IBD | 2− | 75 |
Mansfield et al537 | UK (not specified—circa 1997) | Survey of clinicians and patients | 732 Patients; 6 gastroenterology clinics | Information for patients about IBD | 2− | 64 |
Thompson et al532 | UK (not specified—circa 2003) | Survey of patients and nurses | 402 Patients; 62 nurses | Information for patients undergoing gastroscopy | 2− | 73 |
Hawkey and Hawkey530 | UK (not specified—circa 1989) | Survey of patients | 751 Survey responses | Information for patients with GI diseases | 2− | 70 |
NICE671 | UK (2004) | Summary of guidelines | NA | Information leaflet for patients | 3 | 30 |
Greiner et al536 | USA (2002) | Survey of patients | Not clear—around 800 patients | Barriers to colorectal cancer screening | 2− | 70 |
Institute of Food Research529 | UK (2004) | Information and advice to the public | NA | Diet and health | 3 | 41 |
Mukherjee et al528 | UK (not specified—circa 2001) | Qualitative study | 24 Patients | Parents’ experiences of IBD | 2− | 75 |
Section 4.6.6 Diagnosis and complications in care
|
Jenkins541 | UK (2001) | Commentary, review of evidence | NA | Paediatric IBD | 3 | 52 |
Mamula et al790 | International; emphasis on USA (data between 1977 and 2000 taken) | Analysis of routine data | 82 Patients | IBD in children under 5 years of age | 2− | 70 |
de Dombal544 | International; emphasis on UK (1994) | Commentary; review of evidence | Around 7 articles | Acute abdominal pain | 3 | 57 |
Gatta et al561 | Europe (not specified—data collected between 1988 and 1999) | Analysis of cancer data | 2720 Patients | Colorectal cancer in Europe | 2− | 59 |
Camilleri543 | USA (2001) | Review of evidence; commentary | Around 170 articles | Management of IBS | 3 | 64 |
Limpert et al554 | USA (patients between 1992 and 2002 were used | Analysis of patient data | 181 Patients | Colon and rectal cancer in the elderly | 2− | 61 |
Sanders et al174 | UK (1999–2001) | Cross sectional intervention | 1200 Participants | Diagnosis of coeliac disease | 2+ | 70 |
Spray et al540 | UK (patients between 1994 and 1998 were used) | Analysis of medical records | Around 100 patients | IBD in children | 2+ | 52 |
Hamilton and Sharp556 | UK (evidence between 1966 and 2002 taken) | Assessment of clinical guidelines | Around 100 articles | Guidelines for the diagnosis of colorectal cancer | 2+ | 66 |
Ofman et al545 | USA (not specified—circa 2002) | Application of decision analysis | NA | Management strategies for gastro-oesophageal reflux disease | 2− | 75 |
Brignoli et al548 | Switzerland (not specified—circa 1997) | Case-control study | 1078 Patients | Diagnostic strategies for dyspepsia | 2+ | 70 |
Summerton and Paes549 | UK (1997–98) | Survey; audit | 275 Responses | Clinical assessment of patients with large bowel symptoms | 2− | 70 |
Farmer et al539 | USA (not specified—circa 2000) | Evaluation of practice; analysis of patient data | 119 Patients | Diagnostic accuracy for IBD | 2− | 61 |
Shah et al562 | USA (1995–98) | Review of patient data | 168 Patients | Use of colonoscopy and biopsy | 2− | 61 |
Erickson and Glick563 | International (studies between 1974 and 1982 taken) | Review of evidence | Around 80 articles | Benefits of oesophagogastroduodenoscopy | 2− | 61 |
Drossman et al551 | USA (1996–98) | Survey of patients | 211 Patients | Factors pointing to the severity of functional bowel disorders | 2− | 70 |
Sands et al552 | USA (patients between 1991 and 1997) | Analysis of patient data | 345 Patients | Risk of early surgery for Crohn’s disease | 2+ | 64 |
Lang et al566 | Finland (1996–97) | Observational study | 503 Patients | Resource use in gastroenterological surgery | 2− | 70 |
Tunaci558 | International (2002) | Commentary | NA | Imaging of GI cancers | 3 | 52 |
Quine et al867 | UK (1991) | Audit | 15 Hospitals in East Anglia and northwest England | Audit of upper GI endoscopy | 2− | 59 |
Parry et al564 | UK (not specified—circa 2001) | Retrospective study of patient data | 52 Patients | Push enteroscopy | 2− | 61 |
Diamanti et al550 | Italy (not specified—circa 2002) | Analysis of patient data | 6 Patients | Patients with ultra-short bowel disease | 2− | 52 |
Yasui et al565 | International (cancer cases between 1993 and 1998) | Analysis of cancer cases | 9241 Cases | Molecular-pathological diagnosis of GI tissues for cancer histopathology | 2− | 68 |
Schofield567 | UK (data between 1994 and 1998 taken) | Review of medical cases | 245 Cases | Medical negligence in coloproctology | 3 | 57 |
Hansen et al547 | Denmark (1991–92) | Interview of patients | 612 Patients | Management of dyspeptic patients in primary care | 2− | 70 |
Talley et al546 | International (1991) | Review of evidence | Around 180 articles | Classification and guidelines for the diagnosis and management of functional dyspepsia | 3 | 80 |
Mulcahy et al868 | UK (data between 1989 and 1998 taken) | Retrospective review of patients data | 9795 Patients | Patterns of sedation use for diagnostic gastroscopy | 2− | 55 |
Hin et al378 | UK (1996–97) | Case finding study | 30 Patients | Coeliac disease in primary care | 2− | 66 |
Schmulson and Chang542 | International (1999) | Review of evidence | Around 50 articles | Diagnostic approach to IBS | 3 | 70 |
Martin et al555 | UK (1994) | Analysis of patient data; survey | 115 Patients | Delays in the diagnosis of oesophagogastric cancer | 2− | 61 |
Angelelli et al553 | International (2003) | Review of evidence; commentary | Around 40 articles | Computed tomography and acute bowel ischaemia | 3 | 66 |
Berg et al538 | International (2001) | Review of evidence; commentary | Around 40 articles | Acute surgical emergencies in IBD | 3 | 64 |
Rockey et al869 | USA (2000–04) | Comparison of imaging tests | 614 Patients | Comparison of colon imaging tests | 2+ | 82 |
Halligan and Atkin870 | UK (2005) | Commentary | NA | Virtual colonoscopy | 4 | 55 |
Section 4.7.1 Guidelines for care
|
Chiang et al797 | Australia (2001) | Analysis of patient data | 167 Patients | Acute pancreatitis management | 2+ | 68 |
BSG574 | UK (2002) | Guidelines | NA | Guidelines for dyspepsia management | Guideline | 45 |
Hamilton and Sharp556 | UK (evidence between 1966 and 2002 taken) | Assessment of clinical guidelines | Around 100 articles | Guidelines for the diagnosis of colorectal cancer | 2+ | 66 |
Association of Coloproctology of GB and Ireland505 | UK (2001) | Specification of guidelines | NA | Guidelines for the management of colorectal cancer | Guideline | 61 |
Flashman et al507 | UK (2000–01) | Audit | 249 Patients | Two week standard for bowel cancer | 2− | 61 |
Kubba and Whyman606 | UK (1994) | Survey of clinicians | 81 Responses | Survey of practice amongst Scottish gastroenterologists | 2− | 59 |
DoH605 | UK (2004) | Guidelines | NA | Renal services implementation strategy | Guideline | 45 |
Rockall et al398 | UK (1993) | Analysis of patient data | 2531 Patients | Management of upper GI haemorrhage | 2− | 57 |
Limburg and Ahlquist569 | International; emphasis on USA (2002) | Commentary | NA | Management of colorectal cancer | 4 | 45 |
Ahmed et al571 | International (studies from 1996 onwards) | Systematic review | Four RCTs | Supportive care for patients with GI cancer | 1 | 75 |
McNamara et al581 | International; emphasis on USA (2000) | Review of evidence; expert commentary | Around 70 articles | Non-ulcer dyspepsia (NUD) | 2− | 64 |
Meineche-Schmidt871 | Denmark (1999–2000) | RCT and follow-up | 829 Patients | Healthcare consumption | 2+ | 57 |
Wexner et al600 | USA (2001) | Commentary; consensus | NA | Principles for privileging and credentialing for endoscopy and colonoscopy | 4 | 52 |
Bardou et al572 | USA (1999–2002) | Case-control study | Over 80 000 patients | Treatment of oesophageal cancer | 2+ | 70 |
Bodger et al596 | UK (not specified—circa 1996) | Analysis of physicians’ practice data | 9 GPs | Prescriptions in primary care | 2− | 66 |
Delaney et al579 | International (2003) | Systematic review | 20 RCTs | Management strategies for dyspepsia | 1 | 82 |
Fisher et al599 | USA (1995–1996) | Analysis of patient data | 3546 Patients | Mortality and follow-up colonoscopy after colorectal cancer | 2+ | 61 |
Moum585 | International (2000) | Review of evidence | Around 80 articles | Medical treatment for IBD | 3 | 64 |
Feuer595 | International (1999) | Commentary; review of evidence | Around 20 articles | Management of intestinal obstruction | 3 | 50 |
Conio et al591 | International (2001) | Commentary; review of evidence | Around 80 articles | Endoscopic treatment of pancreatico-biliary malignancies | 3 | 57 |
Talley et al546 | International (1991) | Review of evidence | Around 180 articles | Classification and guidelines for the diagnosis and management of functional dyspepsia | 3 | 80 |
Drossman et al551 | International (not specified—circa 1994) | Survey of patients | 270 Patients | Measuring health status and severity of illness for functional bowel disorders | 2− | 77 |
Jeffery et al568 | International (studies from 1966 onwards) | Systematic review | 5 RCTs | Follow-up strategies for colorectal cancer | 1 | 75 |
Axon et al602 | UK (not specified—circa 1995) | Audit; survey of clinicians | 350 General physicians, 400 surgeons, 477 gastroenterologists, 70 GPs | Guidelines on appropriate indications for upper GI endoscopy | 2+ | 77 |
Allum et al570 | UK (2002) | Review of evidence; recommendations | Around 340 articles | Guidelines for the management of oesophageal and gastric cancer | Guideline | 75 |
Raine et al593 | UK (2002) | Qualitative research into GPs’ beliefs | 46 GPs | GPs’ perceptions of chronic disease syndrome and IBS | 2− | 73 |
Carter et al584 | UK (2004) | Review of evidence; recommendations | Around 150 articles | Guidelines for the management of IBD | Guideline | 75 |
Ryder594 | UK (2003) | Review of evidence; recommendations | Around 150 articles | Guidelines for the diagnosis and treatment of hepatocellular carcinoma | Guideline | 75 |
Verma and Giaffer588 | UK (not specified—circa 2001) | Survey of patients; analysis of patient data | Around 1000 patients | H pylori eradication | 2− | 77 |
Milne et al872 | UK (1993) | Survey of gastroenterologists | 670 Survey responses | H pylori and upper GI disease | 2− | 64 |
Parry et al578 | UK (1995) | Survey of GPs | 140 GPs | GPs’ management of dyspepsia in primary care | 2− | 73 |
Probert et al604 | UK (not specified—circa 1993) | Survey of gastroenterologists | 236 Survey responses | Gastroenterologists’ care profile for patients with IBD | 2− | 61 |
Whitaker et al589 | UK (1997) | Commentary; review of guidelines for care | Around 50 articles | Management of GI disease in primary care | 3 | 59 |
Paton590 | UK (1992–93) | Economic analysis; RCT | 255 Patients | Comparison of two treatments for gastro-oesophageal reflux disease | 2+ | 64 |
Wright et al586 | UK (not specified—circa 2001) | Analysis of patient data | 6037 Patients | Implementation of H pylori eradication therapy | 2− | 61 |
NICE577 | UK (2003) | Guidelines | NA | Managing adult patients with dyspepsia | Guideline | 57 |
Spiegel et al575 | International; emphasis on USA (2002) | Review of guidelines; economic modelling | Around 120 articles | Competing strategies for dyspepsia management | 2− | 75 |
Bodger et al576 | UK (1995–1996) | Observational study | 340 Patients | Implications of BSG dyspepsia guidelines | 2− | 68 |
Association of coloproctology of GB and Ireland505 | UK (1999) | Guidelines for coloproctology | NA | Guidelines for coloproctology | Guideline | 45 |
Manes et al601 | Italy (1998) | Analysis of patient data | 706 Patients | Appropriateness and diagnostic yield of upper GI endoscopy in an open access system | 2− | 64 |
Tremaine et al583 | USA (1997) | Survey and analysis of patient data | Not clear—around 100 patients | Practice guidelines in IBD | 2+ | 61 |
Section 4.7.2 Incidence of cancer
|
Forman et al873 | UK (data up to 1992; published 2003) | Analysis of data | Over 1.5 million cases | Cancer prevalence in the UK | 2− | 66 |
Munkholm814 | International (2003) | Review of evidence; commentary | Around 25 articles | Incidence and prevalence of colorectal cancer | 3 | 57 |
AGA788 | USA (2001) | Review of evidence; expert commentary | Over 125 articles | Prevalence and costs of GI diseases | 2+ | 68 |
Sant et al874 | Europe (2001) | Analysis of routine data | 1 836 287 Patient records | Cancer survival rates | 2− | 57 |
Stanley et al816 | International (1988) | Review of trends | Around 20 articles | Mortality trends | 2− | 59 |
Askling et al875 | Sweden (data between 1952 and 1995 taken) | Analysis of patient data | 114 102 Records | Colorectal cancer rates | 2+ | 52 |
Lynch and de la Chapelle876 | International; emphasis on USA (2003) | Commentary; review of evidence | Around 100 articles | Hereditary colorectal cancer | 3 | 52 |
ONS441 | UK (data between 1991 and 2001) | Update on cancer survival rates | NA | Cancer survival rates | NA | NA |
Sharp et al824 | UK (data between 1968 and 1992) | Analysis of cancer data | Not specified, but a large amount | Cancer incidence and mortality | 2− | 50 |
McKinney et al835 | UK (data between 1960 and 1990) | Analysis of cancer data | Not specified, but a large amount | Oesophageal and gastric cancer incidence | 2− | 52 |
Pye et al825 | UK (1995–96) | Analysis of patient data | 910 Patients | Carcinoma of the oesophagus and stomach | 2− | 57 |
Bray et al328 | Europe (1995) | Analysis of mortality data | Not specified, but a large amount | Cancer incidence and mortality | 2+ | 66 |
Bardou et al572 | USA (1999–2002) | Case-control study | Over 80 000 patients | Treatment of oesophageal cancer | 2+ | 70 |
Rhodes and Campbell877 | International (2002) | Review of evidence | Around 70 articles | Inflammation and colorectal cancer | 3 | 61 |
AUGIS826 | UK (1999) | Commentary and recommendations | NA | Service provision | 4 | 35 |
Section 4.7.4 Screening (includes surveillance)
|
Mpofu et al611 | International; emphasis on UK (2004) | Systematic review | 9 Key reports | Strategies for detecting colon cancer | 1 | 84 |
Rozen et al608 | International (2002) | Expert commentary; recommendations | NA | Worldwide cancer screening | 3 | 73 |
Mandel et al609 | USA (longitudinal study—results from 70s, 80s, and 90s) | Analysis of patient data | 46 551 Participants | Screening for colorectal cancer | 2+ | 64 |
Garvican607 | UK (1998) | Commentary; cost analysis | NA | Colorectal cancer screening | 3 | 70 |
Doria-Rose et al633 | USA (data between 1994 and 2000 taken) | Analysis of patient data | Over 70 000 participants | Screening intervals | 2− | 70 |
Lin et al613 | USA (1999) | Survey of clinical practice | 103 Responses | Current practices in Barrett’s oesophagus | 2− | 73 |
UK Colorectal Cancer Screening Pilot Group610 | UK (2000–03) | Pilot/audit | 271 646 Participants | Screening for colorectal cancer | 2− | 64 |
Hill et al628 | UK (not specified—circa 2000) | Assessment of practice | 109 Families | Screening for colorectal cancer | 2− | 57 |
Kronborg627 | Europe (1992) | Assessment of guidelines | Around 50 articles | Screening guidelines for colorectal cancer | 2− | 68 |
Dubinsky et al623 | USA (2000) | Economic and statistical analyses | Not specified | Economic issues for competing diagnostic strategies | 2− | 75 |
Gerson et al615 | USA (2003) | Economic modelling | Not specified, but a large amount | Cost effectiveness of endoscopic screening and surveillance for GERD | 2− | 73 |
Lewis878 | USA (2000) | Commentary | NA | Screening of colorectal cancer | 4 | 43 |
Macafee and Scholefield632 | UK (2002) | Commentary; review of evidence | Around 40 articles | Screening of colorectal cancer | 3 | 57 |
Ganz et al626 | USA (1999) | Survey; RCT | 36 Provider organisations | Screening of colorectal cancer | 2+ | 68 |
Gross et al612 | USA (1998) | Survey of gastroenterologists | 279 Survey responses | Management of Barrett’s oesophagus | 2− | 80 |
Loeve et al621 | USA (circa 2000—projected data between 1993 and 2023) | Data simulation | Baseline data from routine sources and expert opinion | Colorectal cancer screening | 2− | 77 |
Rae630 | Australia (data between 1987 and 1996 taken) | Analysis of patient data | 3845 Patients | Community screening for colorectal cancer | 2− | 61 |
Nietert et al620 | USA (circa 2002) | Economic modelling | NA | Cost effectiveness of screening for chronic gastroesophageal refulx disease | 2− | 75 |
Ramsey et al617 | USA (data between 1993 and 1999 taken) | Analysis of patient data | 206 Patients | Costs of screening for colorectal cancer | 2− | 70 |
Sonnenberg et al879 | USA (1998) | Economic modelling | NA | Costs of screening for colorectal cancer | 2− | 70 |
Renehan et al618 | UK (2002) | Review of evidence | 5 RCTs | Cost effectiveness of surveillance for colorectal cancer | 2+ | 80 |
Helm et al625 | International; emphasis on USA (not specified—circa 2003) | Review of evidence; commentary | Around 60 articles | Strategies for colorectal cancer screening | 3 | 80 |
Taylor et al629 | UK (not specified—circa 2000) | Survey of patients | 4153 Survey responses | Acceptability of flexible sigmoidoscopy screening | 2− | 64 |
Bejes and Marvel624 | USA (not specified—circa 1992) | Case-control study | 546 Patients | Offering colorectal cancer screening to patients | 2− | 61 |
Cotton et al635 | USA (2000–01) | Non-randomised trial | 615 Patients | Virtual colonoscopy | 2− | 64 |
Hur et al634 | USA (2004) | Mathematical modelling | Data from 1998 to 2002 | Computed tomographic colonography | 2− | 70 |
Section 4.7.5 Genetics
|
Lynch and de la Chapelle876 | International; emphasis on USA (2003) | Commentary; review of evidence | Around 100 articles | Hereditary colorectal cancer | 3 | 52 |
Polito II et al880 | USA (data between 1985 and 1991) | Analysis of patient data | 552 Patients | Genetic anticipation in Crohn’s disease | 2− | 55 |
Yasui et al565 | International (cancer cases between 1993 and 1998) | Analysis of cancer cases | 9241 Cases | Molecular-pathological diagnosis of GI tissues for cancer histopathology | 2− | 68 |
Morris-Yates et al881 | Australia (participants between 1984 and 1986) | Structured interviews of patients; genetic modelling | 686 Individual twins | Genetic contribution to functional bowel disorders | 2− | 70 |
Faybush et al882 | Canada (patient data between 1984 and 1995) | Analysis of patient data | 315 Patients | Generational differences in IBD: genetic, bias, and temporal effects issues | 2− | 59 |
Section 4.7.6 Prevention
|
Chan and Graham512 | International (2004) | Review of evidence | Around 60 articles | Prevention of NSAID GI complications | 3 | 73 |
Muller and Sonnenberg652 | USA (1988–93) | Analysis of patient data | Over 16 000 patients | Prevention of colorectal cancer | 2+ | 55 |
Hulscher et al651 | International (review of studies from 1966 onwards) | Systematic review | 55 Studies | Prevention in primary care | 1 | 77 |
O’Connor and Sebastian654 | Europe (2003) | Review of evidence; commentary | Around 60 articles | Burden of H pylori in Europe | 3 | 50 |
Section 4.7.6 Devolution
|
Greer883 | UK (2004) | Commentary; review of evidence | Around 30 articles | Devolution and the NHS | 3 | 52 |
Section 4.7.7 Managed cancer networks
|
CSCG808 | UK (2003) | Commentary | NA | Response to NICE service guidance on upper GI cancers | Guideline | 41 |
South Wales Cancer Network754 | UK (2003) | Service guidelines; recommendations | NA | Configuration of services | 3 | 45 |
Section 4.7.8 Quality assessment
|
Garvican607 | UK (1998) | Commentary; cost analysis | NA | Colorectal cancer screening | 3 | 70 |
Association of Coloproctology of GB and Ireland505 | UK (2001) | Specification of guidelines | NA | Guidelines for the management of colorectal cancer | Guideline | 61 |
Lilford et al884 | UK (not specified—circa 2004) | Review of evidence | Around 90 articles | Managing performance in acute medical care | 3 | 73 |
Rockall et al885 | UK (1993–94) | Collection and analysis of patient data | Over 5000 cases | Outcomes after acute upper GI haemorrhage | 2− | 57 |
Johansen et al886 | USA (applicable internationally) (2000) | Commentary | NA | Quality and outcomes assessment in GI endoscopy | 3 | 45 |
Dougall et al887 | UK (1997) | Survey of patients | 84 Patients | Patient experiences of an open access flexible sigmoidoscopy service | 2− | 77 |
Feuer and Broadley888 | International (studies from 1966 onwards) | Systematic review | 25 Articles | Surgery for malignant bowel obstruction in GI cancers | 2+ | 73 |
Fletcher889 | Australia (1997) | Review of evidence | Around 40 articles | Management of peptic disease | 3 | 64 |
Bodenheimer et al890 | USA (2002) | Case study | Four healthcare organisations | Improving primary care for chronic illness | 3 | 61 |
van der Eijk et al891 | International (2000) | Literature review | Around 80 articles | Quality of care in IBD | 3 | 68 |
Gilmore et al892 | UK (1991) | Audit | 1500 Completed audit forms | Audit of liver biopsy | 2− | 61 |
Jones809 | International (1999) | Review of evidence | Around 20 articles | Methodological considerations | 3 | 68 |
McCulloch et al829 | UK (1999–2002) | Cohort study; analysis of patient data | 955 Patients | Mortality and morbidity in gastro-oesophageal cancer surgery | 2− | 64 |
Kurlberg et al893 | Sweden (2004) | Commentary | NA | Access to patient information | 3 | 43 |
Bass et al695 | UK (1994) | Analysis of patient data | 762 Patients | Frequent attendants at a gastroenterology clinic | 2− | 61 |
Palmer and Morris894 | UK (2004) | Commentary | NA | Colonoscopy practice in England | 4 | 41 |
Bowles et al752 | UK (not specified—circa 2003) | Survey of clinicians and patients | 9223 Cases | Colonoscopy practice in the UK | 2− | 66 |
Macarthur et al895 | UK (1993) | Audit of deaths from large bowel surgery | 187 Cases | Deaths from large bowel surgery | 2− | 61 |
van der Eijk et al896 | International (1998) | Observational study/survey | Physicians and health workers from 8 countries | Best practice in IBD | 2− | 73 |
Eaden et al897 | UK (not specified—circa 1998) | Survey of clinicians | 341 Responses | Screening for colonic cancer by gastroenterologists | 2− | 64 |
Section 5.1 Where should services be provided (primary, secondary, tertiary—includes patient roles)?
|
Scott et al898 | Canada (not specified—circa 2003) | Survey of patients | 14 Patients | Use of complementary therapies for IBD | 2− | 55 |
Hinton899 | UK (not specified—circa 1994) | Survey | 415 Patients; focus on 77 of these | Transfer of care from home to hospital | 2− | 45 |
Shepperd and Iliffe689 | International (1996–2001) | Systematic review | 16 Trials | Hospital versus home care | 1 | 66 |
Barrett et al900 | UK (1998–99) | Retrospective study; analysis of routine data | 903 Patients | Description of intermediate care service | 2− | 57 |
Gill and Martin901 | New Zealand (1995–97) | Analysis of patient data | 3351 Patients | Distance from hospital | 2− | 59 |
South Wales Cancer Network754 | UK (2003) | Service guidelines; recommendations | NA | Configuration of services | 3 | 45 |
Whynes and Thornton902 | UK (not specified—circa 1998) | Economic/statistical analysis | Not clear—data for around 18 wards | Concentration in primary care | 2− | 61 |
Section 5.2 What types of services should be provided (includes current provision)?
|
Gonsalkorale et al903 | UK (not specified—circa 2002) | Survey of patients | 232 Patients | Hypnotherapy in IBS | 2− | 75 |
van Dam et al904 | Not specified—probably international (not specified—circa 2004) | Review of clinical trials | Review of around 10 papers | Review of computerised tomographic colonography (CTC) | 2+ | 70 |
Podolsky905 | Not specified—probably international (2004) | Expert commentary | NA | CTC | 4 | 41 |
Silcock and Bramble502 | UK (1994) | Survey | 333 Responses | Survey of current practice in open access gastroscopy (OAG) | 2− | 68 |
Baron et al906 | USA (2002–03) | Cohort study | 498 Patients | Demand for colonoscopy | 2+ | 66 |
Cheung et al907 | UK (1999) | Survey and structured interviews | 160 GPs | Shared care in gastroenterology | 2− | 61 |
Moody et al772 | UK (not specified—circa 1993) | Survey of GPs | 259 Responses | GPs views on requirements for gastroenterology services | 2− | 70 |
Smith et al908 | UK (not specified—circa 2000) | Survey of patients | 100 Responses | Impact of a nurse-led counselling service | 2− | 68 |
Ilnyckyj et al909 | Canada (1996–1997) | Observational study | 70 Patients | Gastroenterology consultation | 2− | 64 |
Pasricha910 | Not specified—probably international (2004) | Expert commentary | NA | Future of therapeutic endoscopy | 3 | 52 |
Axon911 | UK (1998) | Expert commentary | NA | Open access endoscopy in Britain | 4 | 50 |
DoH912 | UK (2001) | National commentary; recommendations | NA | Upper GI cancers | Guideline | 48 |
Richards et al760 | International (1997) | Systematic review | 256 Studies | Home parenteral nutrition (HPN) | 1 | 77 |
Talley and Spiller913 | International (not specified—circa 2002) | Review of evidence | Around 140 studies | IBS | 3 | 70 |
Nord914 | USA (1999) | Expert commentary | NA | Developments in Endoscopy | 4 | 57 |
Jones770 | UK (1996) | Expert commentary | NA | GI disease in primary care | 3 | 59 |
van der Eijk et al896 | International (1998) | Observational study/survey | Physicians and health workers from 8 countries | Best practice in IBD | 2− | 73 |
Abuksis et al915 | Israel (1998) | RCT | 142 Patients | A patient education programme | 2+ | 68 |
Lewin van den Broek et al916 | Netherlands (1995–97) | RCT | 349 Patients | Management strategies for dyspepsia | 2+ | 66 |
Delaney and Moayyedi917 | Predominantly UK (not specified—circa 2003) | Evidence-based assessment | Around 160 articles | Dyspepsia management | 2− | 57 |
Heaney et al918 | UK (1993–96) | Analysis of patient and GP data | 1872 Cases | Open access gastroscopy in Royal Victoria Hospital, Belfast | 2− | 55 |
Pye et al825 | UK (1995–96) | Analysis of patient data | 910 Patients | Carcinoma of the oesophagus and stomach | 2− | 57 |
Association of Coloproctology of GB and Ireland505 | UK (2001) | Specification of guidelines | NA | Guidelines for the management of colorectal cancer | Guideline | 61 |
Hansen et al919 | Denmark (1987–88) | Survey of patients and GPs | 436 Patients | Efficacy of open access endoscopy | 2− | 68 |
Section 5.3 Who should deliver/perform services and/or procedures (for example, endoscopies)?
|
Eaden et al897 | UK (not specified—circa 1998) | Survey of clinicians | 341 Responses | Screening for colonic cancer by gastroenterologists | 2− | 64 |
Paisley et al920 | UK (1994–96) | Analysis of patient data | 222 Patients | Role of the surgical trainee | 2− | 59 |
Chin and Newton921 | UK (not specified—circa 1996) | Survey | 167 Surgical trainees | Training in minimal access surgery | 2− | 66 |
Pardo et al922 | Spain (1998–99) | Retrospective study; analysis of patient data | 620 Patients | Impact of physician speciality | 2− | 61 |
Waye et al923 | International (2001) | Expert commentary | NA | Who is permitted to do endoscopy? | 4 | 36 |
Bini et al924 | USA (1998–99) | Analysis of routine data | 197 Patients | Impact of specialists | 2− | 68 |
Eaden et al925 | UK (data between 1985 and 1999 taken) | Survey of clinicians | 13 Clinicians | Variation between generals and specialists | 2− | 68 |
Barrison et al926 | UK (2001) | Expert commentary and recommendations | NA | Provision of endoscopy services in general hospitals | 4 | 45 |
Quine et al521 | UK (1991) | Survey of clinicians | 39 Hospitals; 383 clinicians | Audit of upper GI endoscopy | 2− | 64 |
NHS CRD560 | UK (2004) | National commentary; guidelines; recommendations | NA | Improving the outcomes in colorectal cancer | Guideline | 70 |
Lim et al927 | UK (1995) | Survey of clinicians | 453 Responses | H pylori serology and management | 2− | 68 |
Cockel et al928 | UK (1976–79) | Survey | 173 Responses | GI endoscopy services | 2− | 66 |
Meyer et al710 | USA (1993) | Analysis of patient data | Over 1.3 million cases | Differences between generalists and specialists | 2− | 68 |
Knight-Davis et al929 | UK (1996) | Survey of clinicians | 350 Responses | Cross-cover for physicians | 2− | 59 |
Association of Coloproctology of GB and Ireland753 | UK (2001) | Analysis of audit data; expert commentary; recommendations | 8 Main sources of audit data | Resources for coloproctology | 3 | 52 |
Chen and Rex717 | International (2004) | Commentary; recommendations | NA | Nurse administered sedation for endoscopy | 3 | 59 |
Nightingale and Hogg930 | UK (2003) | Review of evidence; commentary | Around 40 articles | GI advanced practitioners | 3 | 64 |
Section 5.4 What are the key issues concerning changing roles and general practitioners with a special interest (GPwSI)?
|
Farthing et al931 | UK (1993) | Peer reviewed expert commentary and recommendations | NA | Service provision | 3 | 59 |
Colin-Thome932 | UK, NHS (2002) | Commentary | NA | GPwSI | 4 | 43 |
Birch933 | UK, NHS (2004) | Commentary; guidelines | NA | GPwSI | 3 | 52 |
AUGIS826 | UK (1999) | Commentary; recommendations | NA | Service provision | 4 | 35 |
Pearson et al934 | Boston, USA (1996) | Survey of general internists and gastroenterologists | 91 Survey responses | Study of consultations provided to general internists by gastroenterologists. | 2− | 75 |
Williams et al935 | UK (2002) | Commentary; recommendations | NA | The role of GPwSI | 3 | 66 |
DoH and RCGP691 | UK (2003) | Commentary; recommendations | NA | Implementing GPwSI | Guideline | 45 |
DoH and RCGP936 | UK (2002) | National guidelines | NA | GPwSI roles | Guideline | 25 |
Ryan937 | UK (2002) | Commentary | NA | Role of GPwSI in respiratory disease | 4 | 30 |
Gruffydd-Jones938 | UK (2003) | Brief commentary | NA | Framework for GPwSI | 3 | 55 |
Kernick939 | UK (2003) | Commentary | NA | Economic perspectives on GPwSI | 4 | 52 |
Richardson940 | UK (2002) | Commentary; interviews | NA | Rise of GPwSI | 4 | 50 |