Table 3.2.6 Incidence and prevalence rates (per 100 000 population) for primary biliary cirrhosis as reported from various studies in the UK, and in other countries

Country	Region	Study period	Study sources*	No of cases	Incidence per 100 000 population	Prevalence per 100 000 population	Authors and reference
*Study sources: SP, survey of physicians; Lab, laboratory data on subjects with AMA; HR, review of hospital records or admission data; LHD, liver history data; ND, notification of deaths.
UK studies:
UK	Sheffield	1976–79	SP, Lab	34	0.6	5.4	Triger DR, 1980²³⁹
UK	Northern England	1976–87	SP, Lab, HR	347	1.9	1.8 in 1976 12.9 in 1987	Myszor M and James OF, 1990²³⁷
UK	Dundee	1975–79	LHD	29	1.1	4.0	Hislop WS et al, 1982²⁴⁰
UK	NE England	1972–79	SP	117	1.0	3.7 (rural)14.4 (urban)	Hamlyn AN et al, 1983²⁴¹
UK	Glasgow	1965–80	Lab, LHD	373	1.1–1.5	7.0–9.3	Goudie BM et al, 1987²⁴²
UK	Northern England	1987–94	SP, Lab, HR, LHD, ND	770	2.3 in 1987 3.2 in 1994	20.2 in 1987 34.5 in 1994	James OF et al, 1999²³⁸
UK	Newcastle	1987–94	SP, Lab, HR, LHD, ND	160	2.2	18.0 in 1987	Metcalf JV et al, 1997²⁴³
						24.0 in 1994
UK	Swansea	1995–96	Lab, HR, LHD	67	–	20.0	Kingham JG and Parker DR, 1998²⁴⁴
Foreign studies:
Sweden	Umea	1972–83	SP, Lab, HR	86	1.3	15.1	Danielsson A et al, 1990²⁴⁵
Sweden	Malmo	1973–82	Lab, HR, ND	33	1.4	9.2 in 1982	Eriksson S and Lindgren S, 1984²⁴⁶
Sweden	Orebro	1976–83	Lab	36	1.4	12.8 in 1983	Lofgren J et al, 1985²⁴⁷
Europe	10 centres	1981	SP	569	–	2.3 (0.5–7.5)	Triger DR et al, 1984²⁴⁸
Canada	Ontario	1986	SP	206	0.3	2.2	Witt-Sullivan H et al, 1990²⁴⁹
Spain	Granada	1976–89	SP, HR	25	4.1	3.6 in 1976	Caballero Plasencia AM et al, 1991²⁵⁰
						6.2 in 1989
Australia	Victoria	1991	SP, HR	84	–	1.9	Watson RG et al, 1995²⁵¹
Norway	Oslo	1986–95	HR	25	1.6	14.6 in 1995	Boberg KM et al, 1998²⁵²
Estonia		1973–92	SP, Lab	69	0.2	2.7	Remmel T et al, 1995²⁵³
USA	Olmsted County	1976–2000	Lab, HR	22	1.3 in men 0.5 in women	6.3 in women	Bambha K et al, 2003²⁵⁴
Alaska		1984–2000	Lab, HR	18	–	16 (natives)	Hurlburt KJ et al, 2002²⁵⁵
Australia	Victoria	1990–2002	SP, Lab, HR	249	–	5.1	Sood S et al, 2004²⁵⁶