| BMI | Controls/cases | Oesophageal adenocarcinoma | Gastro-oesophageal junction adenocarcinoma | |||
| Fully adjusted, except reflux* | Fully adjusted, with reflux† | Cases | Fully adjusted, except reflux | Fully adjusted, with reflux | ||
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |||
| Women | ||||||
| <25.0 | 224/12 | 1.0 (ref) | 1.0 (ref) | 16 | 1.0 (ref) | 1.0 (ref) |
| 25.0–29.9 | 166/8 | 0.5 (0.2 to 1.5) | 0.5 (0.2 to 1.5) | 18 | 1.0 (0.6 to 2.7) | 1.2 (0.5 to 2.5) |
| ⩾30.0 | 125/13 | 1.7 (0.7 to 4.1) | 1.4 (0.5 to 3.5) | 22 | 2.3 (1.1 to 4.7) | 1.9 (0.9 to 4.1) |
| Men | ||||||
| <25.0 | 325/60 | 1.0 (ref) | 1.0 (ref) | 92 | 1.0 (ref) | 1.0 (ref) |
| 25.0–29.9 | 484/142 | 1.6 (1.1 to 2.2) | 1.3 (0.9 to 1.9) | 150 | 1.1 (0.8 to 1.5) | 1.0 (0.7 to 1.4) |
| ⩾30.0 | 189/117 | 3.3 (2.3 to 4.8) | 2.6 (1.8 to 3.9) | 112 | 2.1 (1.5 to 2.9) | 1.7 (1.2 to 2.5) |
| Age <50 years | ||||||
| <25.0 | 127/5 | 1.0 (ref) | 1.0 (ref) | 9 | 1.0 (ref) | 1.0 (ref) |
| 25.0–29.9 | 94/10 | 1.8 (0.5 to 6.7) | 1.4 (0.3 to 5.5) | 20 | 1.8 (0.7 to 4.7) | 1.3 (0.5 to 3.8) |
| ⩾30.0 | 49/14 | 10.5 (2.7 to 40.9) | 7.5 (1.7 to 33.0) | 14 | 3.9 (1.3 to 11.6) | 3.5 (1.1 to 11.4) |
| Age ⩾50 years | ||||||
| <25.0 | 422/67 | 1.0 (ref) | 1.0 (ref) | 99 | 1.0 (ref) | 1.0 (ref) |
| 25.0–29.9 | 556/140 | 1.4 (1.0 to 2.0) | 1.2 (0.9 to 1.7) | 148 | 1.1 (0.8 to 1.5) | 1.0 (0.7 to 1.3) |
| ⩾30.0 | 265/116 | 2.8 (1.9 to 3.9) | 2.2 (1.5 to 3.1) | 120 | 1.9 (1.4 to 2.7) | 1.6 (1.2 to 2.3) |
*Adjusted for age (in years), sex, state of residence, household income, cumulative smoking history, mean alcohol consumption and frequency of aspirin use in the 5 years before diagnosis.
†Adjusted for above factors and frequency of gastro-oesophageal reflux symptoms 10 years before diagnosis.