| Day 3 variable | IVCS response (n = 53) | IVCS failure (n = 46) | Odds ratio (95% CI)* |
| Nocturnal diarrhoea (episodes/per night) | 20.6 (4.9 to 87) | ||
| None | 25 (47%) | 2 (4%) | |
| 1–2 | 28 (53%) | 30 (65%) | |
| >2 | 0 (0%) | 14 (31%) | |
| Stools per 24 h | 4.2 (4.3 to 7.7) | ||
| 0–2 | 22 (42%) | 4 (9%) | |
| 3–5 | 25 (47%) | 14 (30%) | |
| 6–8 | 5 (9%) | 14 (30%) | |
| >8 | 1 (2%) | 14 (30%) | |
| Blood in stool | 3.5 (1.8 to 7.1) | ||
| None or small amount infrequently | 10 (19%) | 2 (4%) | |
| Small amount in majority of stools | 24 (45%) | 10 (22%) | |
| Large amount in the majority of stools | 19 (36%) | 34 (74%) | |
| Temperature (>37.8°C)*** | 4 (8%) | 9 (20%) | 2.9 (0.8 to 10.4) |
| Abdominal tenderness† | 6 (11%) | 11 (24%) | 2.5 (0.8 to 7.3) |
| PUCAI score | 50 (SD 17) | 70 (SD 14) | 2.2 (1.5 to 3.1)** |
| Seo score | 194 (SD 34) | 226 (SD 30) | 1.4 (1.2 to 1.6)** |
| Lindgren score | 4.2 (SD 2.3) | 9.4 (SD 4.3) | 1.6 (1.3 to 1.9) |
| Travis score | |||
| Positive | 0 (0%) | 17 (38%) | 31 (3.9 to 666) |
| Negative | 53 (100%) | 29 (62%) | |
| Blood tests | |||
| Albumin | 33 (SD 5.7) | 30 (SD 4.4) | 0.53 (0.4 to 0.8)†† |
| CRP (mg/dl) | 0.71 (SD 0.53) | 1.87 (SD 1.57) | 6.2 (2.6 to 14.9) |
| ESR | 38 (SD 22) | 50 (SD 25) | 1.3 (1.03 to 1.5)** |
| Haemoglobin (g/l) | 101 (SD 22) | 97 (SD 17) | 1 (0.97 to 1.01) |
| Platelets (×109/litre) | 452 (SD 142) | 496 (SD 158) | 1 (0.99 to 1.01)** |
Count (%), median (interquartile range) or mean (SD) are presented as appropriate for the data distribution.
*Obtained by an unadjusted logistic regression, without dummy variables.
**Calculated for a 10-unit change.
***Temperature was measured orally.
†Judged as at least mild tenderness by the physician.
††Calculated for a 5-unit change.
PUCAI, Pediatric Ulcerative Colitis Activity Index; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein.