Table Relationship of oesophageal mucosal status to fundic leptin in multivariate analysis
Status of oesophageal epitheliumNumber of subjectsMedian (IQR) fundic leptin (pg/mg)OR (95% CI)*p Value
Normal44126 (78–221)1.00–
Inflamed24114 (76–195)0.99 (0.61 to 1.6)0.99
Barrett’s20202 (123–333)3.39 (1.5 to 7.6)0.003

  • *Odds of having either inflamed or Barrett’s esophagus compared with normal oesophagus (no pathology) for every twofold increase in fundic leptin. Analysis controls for patient age, ethnicity, body mass index, use of proton pump inhibitors and gastric pH.

  • IQR, interquartile range.