Table 1 Characteristics of the study population
ParametersAll casesMSSMSI-Hp Value*
(n = 45)(n = 31)(n = 14)
n (%)n (%)n (%)
Gender (F)21 (47)11 (35)10 (71)0.05
Mean age at surgery (SD)69.7 (1.5)68.8 (1.8)71.8 (2.8)0.40
Right-sided tumour19 (42)9 (29)10 (71)0.01
No or poor differentiation27 (60)20 (70)7 (50)0.21
Mucous component4 (1)0 (0)4 (40)0.01
Lymphocyte infiltration†14 (31)1 (3)13 (93)0.0001
Tumour staging
    pT 1–24 (9)2 (6)2 (14)
    pT 327 (60)16 (52)11 (79)
    pT 414 (31)13 (42)1 (7)0.05
    N026 (58)15 (48)11 (79)
    N1–219 (42)16 (52)3 (21)0.10
Synchronous metastasis22 (49)19 (61)3 (21)0.02
Vascular emboli25 (56)20 (65)5 (36)0.03
Perinervous infiltration7 (16)5 (16)2 (14)1
Relapse within 36 months of follow-up10 (22)8 (26)2 (14)0.47‡
  • *p Value of Fisher exact test or Mann–Whitney test as appropriate. †Assessed by histopathology evaluation (yes = + to ++; no = 0 to +/−). ‡p Value of log-rank test for equality of survivor functions.

  • F, female, MSS, microsatellite stability; MSI-H, high-frequency microsatellite instability.