Table 2

The list of upregulated miRNAs (change >2-fold as a cut-off level) in plasma and biopsy samples of colorectal cancer (CRC) compared to healthy controls, identified using real-time polymerase chain reaction-based miRNA profiling arrays

Plasma from 5 patients with CRC vs 5 healthy controls			CRC vs adjacent normal biopsies from 5 patients with CRC
MicroRNA	MirBase no	Average fold change	MicroRNA	MirBase no	Average fold change
miR-153	MIMAT0000439	9.81	miR-18a	MIMAT0000072	4.21
miR-373	MIMAT0000726	9.60	miR-224	MIMAT0000280	3.69
miR-204	MIMAT0000265	9.20	miR-223	MIMAT0000279	3.54
miR-202	MIMAT0002811	9.15	miR-135b	MIMAT0000758	3.12
miR-181c	MIMAT0000258	8.10	miR-95	MIMAT0000094	2.87
miR-137	MIMAT0000429	7.39	miR-106a	MIMAT0000103	2.81
miR-125a	MIMAT0000443	7.38	miR-19a+b*	MIMAT0000231, MIMAT0000263	2.75
miR-218	MIMAT0000275	6.65	miR-17-3p	MIMAT0000071	2.72
miR-135b	MIMAT0000758	6.54	miR-20a	MIMAT0000462	2.58
miR-210	MIMAT0000267	5.85	miR-92	MIMAT0000092	2.38
miR-206	MIMAT0000462	5.76	miR-221	MIMAT0000077	2.24
miR-181d	MIMAT0002821	5.54	miR-106b	MIMAT0000680	2.23
miR-203	MIMAT0000264	5.37	miR-222	MIMAT0000279	2.18
miR-200b	MIMAT0000318	5.35
miR-92	MIMAT0000092	4.45
miR-222	MIMAT0000279	4.58
miR-200a	MIMAT0000682	4.45
miR-132	MIMAT0000426	4.34
miR-155	MIMAT0000646	4.29
miR-17-3p	MIMAT0000071	4.17
miR-181b	MIMAT0000257	3.92
miR-136	MIMAT0000448	3.88
miR-200c	MIMAT0000617	3.73
miR-134	MIMAT0000447	3.39
miR-133a	MIMAT0000427	3.37
miR-125b	MIMAT0000423	3.32
miR-183	MIMAT0000261	3.10
miR-95	MIMAT0000094	3.04
miR-128b	MIMAT0000676	3.00
miR-205	MIMAT0000266	2.93

The five markers upregulated in both plasma and CRC biopsies are given in bold type. *Co-detection of miRNA family members in this miRNA profiling array.