Table 1 Baseline characteristics of patients
Variables (No)High VFA group (n = 27)Control group (n = 35)p Value
Age*67.5 (8.9)69.6 (9.7)0.37§
Male16 (59.3%)24 (68.6%)0.59‡
Diabetes mellitus13 (48.1%)14 (40.0%)0.52‡
Dyslipidaemia7 (25.9%)8 (22.9%)0.78‡
BMI (kg/m2)*26.9 (3.8)23.8 (3.2)0.001§
VFA (cm2)*152.1 (45.2)79.0 (29.9)0.001§
SFA (cm2)*180.2 (96.0)113.9 (56.2)0.001§
Waist circumference (cm)*92.5 (10.0)84.2 (10.6)0.001§
Serum albumin (g/dl)†3.9 (3.5–4.2)3.8 (3.4–4.1)0.40§
AST (IU/l)†39.0 (27.5–50.0)38.0 (24.5–53.5)0.94§
Total bilirubin (mg/dl)†0.8 (0.6–1.0)0.8 (0.6–1.5)0.31§
Platelet count (×103/μl)135 (102–187)137 (122–189)0.96§
Prothrombin activity (%)†75.0 (67.5–83.8)78.0 (63.3–88.8)0.68§
Child–Pugh classification0.30¶
    Class A22 (81.5%)26 (74.3%)
    Class B5 (8.5%)6 (17.1%)
    Class C0 (0%)3 (8.6%)
HBcAb positive8 (29.6%)10 (28.6%)0.93‡
Tumour size (mm)*32.1 (15.1)27.6 (15.8)0.26§
Number of nodules0.45‡
    UninodularUninodular16 (59.3%)24 (68.6%)
    MultinodularMultinodular11 (40.7%)11 (31.4%)
AFP >100 ng/ml4 (14.8%)6 (17.1%)0.80‡
DCP >100 mAU/ml5 (18.5%)7 (20.0%)0.88‡
AFP-L3 >15%4 (14.8%)6 (17.1%)0.80‡
  • *Expressed as mean (SD). †Expressed as median (25th–75th percentiles). ‡χ2 tests. §Unpaired Student t test. ¶Cochran–Armitage test.

  • AFP, alpha-fetoprotein; AFP-L3, lens culinaris agglutinin-reactive fraction of AFP; AST, aspartate transaminase; BMI, body mass index; DCP, des-gamma-carboxy prothrombin; HBcAb, hepatitis B core antibody; SFA, subcutaneous fat area; VFA, visceral fat area.