Association between the four single nucleotide polymorphisms (SNP) studied and ulcerative colitis (UC) showing significant reduction of the minor allele frequency in UC

SNP	A1	A2	Dutch UC: 813 cases, 929 controls
SNP	A1	A2	MAF controls	MAF cases	p Value	OR (95%CI)
rs13151961	G	A	0.19	0.14	0.00003	0.67 (0.56 to 0.81)
rs13119723	G	A	0.16	0.12	0.00038	0.71 (0.58 to 0.86)
rs6840978	T	C	0.22	0.16	0.00001	0.68 (0.57 to 0.81)

MAF, minor allele frequency.