Table 2

Comparison between patients with fibrosis stages 0–2 and 3–4

Characteristic	No/mild fibrosis (stage 0–2)	Advanced fibrosis (stage 3–4)	p Value
Age (years)	49±12	61±8	<0.001^*
Gender (%male)	65%	41%	0.02^‡
BMI (kg/m²)	35±5	36±7.6	0.13^*
BMI ≥28	96%	100%	0.58^‡
Diabetes	49%	56%	0.54^‡
Waist circumference (cm)	111±11	113±12	0.34^*
ALT (IU/l)	101±66	68±40	0.001^*
AST (IU/l)	63±44	67±43	0.65^*
GGT (IU/l)	122±109	262±398	0.08^*
ALB (g/l)	45±3	44±9	0.6^*
Platelets (×10⁹/litre)	267±90	204±78	0.001^*
Cholesterol (mmol/l)	5.5±1.3	4.8±1.3	0.01^*
Trigycerides (mmol/l)	2.9±2.4	1.8±0.9	<0.001^*
APRI	0.65±0.52	0.94±0.58	0.01^*
AST/ALT ratio	0.67±0.23	1.05±0.39	<0.001^*
BARD score	2 (0–4)	3 (1–4)	<0.001^†
Fib-4 score	1.25±0.79	2.83±1.71	<0.001^*
NAFLD score	−1.83±1.52	1.52±1.75	<0.001^*

↵* Student t test.
↵† Mann–Whitney U test.
↵‡ χ² test.
ALB, albumin; ALT, alanine aminotransferase; APRI, AST-to-platelet ratio index; AST, aspartate aminotransferase; BMI, body mass index; GGT, gamma-glutamyl transferase; NAFLD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis.