A comparison of the performance of each test for the diagnosis of advanced fibrosis in 145 patients with non-alcoholic fatty liver disease (NAFLD)
| Test | AUROC (95% CI) | Cut-off | Sens (%) | Spec (%) | PPV (%) | NPV (%) |
| AST/ALT ratio | 0.83 (0.74 to 0.91) | 0.8 | 74 | 78 | 44 | 93 |
| 1 | 52 | 90 | 55 | 89 | ||
| APRI | 0.67 (0.54 to 0.8) | 1 | 27 | 89 | 37 | 84 |
| BARD score | 0.77 (0.68 to 0.87) | 2 | 89 | 44 | 27 | 95 |
| FIB-4 score | 0.86 (0.78 to 0.94) | 1.30 | 85 | 65 | 36 | 95 |
| 3.25 | 26 | 98 | 75 | 85 | ||
| NAFLD fibrosis score | 0.81 (0.71 to 0.91) | −1.455 | 78 | 58 | 30 | 92 |
| 0.676 | 33 | 98 | 79 | 86 |
ALT, alanine aminotransferase; APRI, AST-to-platelet ratio index; AST, aspartate aminotransferase; AUROC, area under the receiver operating characteristic curve; PPV, positive predictive value; NPV, negative predictive value; Sens, sensitivity; Spec, specificity.