Worst histological diagnosis in work-up biopsies and endoscopic resection (ER) specimens from subsequent ER sessions
| Work-up biopsies (n=142) | Worst histology 1st ER (n=169) | Worst histology 2nd ER (n=121) | Worst histology 3rd ER (n=71) | Worst histology 4th ER (n=18) | Worst histology 5th ER (n=4) | Worst histology 6th ER (n=1) | Worst histology overall (n=169) | |
| Submucosal cancer | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 7 |
| Intramucosal cancer | 54 | 67 | 7 | 4 | 1 | 1 | 0 | 69 |
| High-grade IN | 88 | 70 | 28 | 11 | 5 | 1 | 0 | 71 |
| Low-grade IN | 0 | 13 | 33 | 12 | 0 | 0 | 0 | 10 |
| No neoplasia | 0 | 12 | 53 | 44 | 12 | 2 | 1 | 12 |
Note: In 27 patients with macroscopic lesions suspicious for cancer, no work-up biopsies were obtained prior to treatment. All 27 patients had high-grade intraepithelial neoplasia (HGIN)/cancer in ER specimens from the first ER session. IN: intraepithelial neoplasia.