Summary of results for the graded response score (GRS)
| Criterion value | ||||||
| 0 | 1 | 2 | 3 | 4 | 5 | |
| <20% reduction in parenteral support | Off parenteral support | |||||
| Placebo | 15 (94%) | 0 (0%) | 1 (6%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Teduglutide 0.10 mg/kg/day | 24 (75%) | 2 (6%) | 4 (13%) | 0 (0%) | 2 (6%) | 0 (0%)* |
| Teduglutide 0.05 mg/kg/day | 19 (54%) | 6 (17%) | 6 (17%) | 0 (0%) | 2 (6%) | 2 (6%) |
Number (%) of patients within the criterion value groups.
Comparison of 0.10 mg/kg/day of teduglutide vs placebo, p=0.16. Comparison of 0.05 mg/kg/day teduglutide vs placebo, p=0.007. p Value based on a rank ANCOVA adjusting for multiple comparisons in the primary efficacy analysis.
↵* One patient was weaned off parenteral support at week 24 with a score of 4.
For GRS score, refer to table 1.